Mukundi Eric, Gomez-Cano Fabio, Ouma Wilberforce Zachary, Grotewold Erich
Center for Applied Plant Sciences (CAPS), The Ohio State University, Columbus, OH, USA.
Molecular, Cellular and Developmental Biology Graduate Program, The Ohio State University, Columbus, OH, USA.
Methods Mol Biol. 2017;1629:207-223. doi: 10.1007/978-1-4939-7125-1_14.
Developing a knowledge base that contains all the information necessary for the researcher studying gene regulation in a particular organism can be accomplished in four stages. This begins with defining the data scope. We describe here the necessary information and resources, and outline the methods for obtaining data. The second stage consists of designing the schema, which involves defining the entire arrangement of the database in a systematic plan. The third stage is the implementation, defined by actualization of the database by using software according to a predefined schema. The final stage is development, where the database is made available to users in a web-accessible system. The result is a knowledgebase that integrates all the information pertaining to gene regulation, and which is easily expandable and transferable.
为研究特定生物体基因调控的研究人员开发一个包含所有必要信息的知识库可以分四个阶段完成。这始于定义数据范围。我们在此描述所需的信息和资源，并概述获取数据的方法。第二阶段包括设计模式，这涉及在系统计划中定义数据库的整个布局。第三阶段是实施，通过使用软件根据预定义的模式实现数据库来定义。最后阶段是开发，在这个阶段，数据库在一个可通过网络访问的系统中提供给用户。结果是一个整合了所有与基因调控相关信息的知识库，并且易于扩展和转移。
