比较磁共振特征跟踪与 CSPAMM HARP 评估全局和局部特定层应变。

Comparison of magnetic resonance feature tracking with CSPAMM HARP for the assessment of global and regional layer specific strain.

机构信息

Department of Radiology, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany.

出版信息

Int J Cardiol. 2017 Oct 1;244:340-346. doi: 10.1016/j.ijcard.2017.06.026. Epub 2017 Jun 8.

DOI:10.1016/j.ijcard.2017.06.026

PMID:28624332

Abstract

PURPOSE

Layer specific strain assessment is increasingly being employed clinically. Cardiac magnetic resonance (MR) Feature Tracking (FT) is considered to be an adequate alternative for strain assessment. The aim of this study is to investigate the feasibility of FT derived layer specific strain assessment.

METHODS

CSPAMM and SSFP-Cine sequences were acquired in 38 individuals (19 patients with HFpEF, 19 controls) in identical midventricular short-axis locations. Global endocardial-, midmyocardial-, epicardial- peak systolic circumferential strain (PSCS) and regional epicardial PSCS were calculated and intra- as well inter-observer variability were assessed.

RESULTS

FT derived global epicardial and endocardial PSCS (7.9±2.3%; -19.6±4.9%) were significantly lower than tagging derived global epicardial and endocardial PSCS (-13.2±2.8%; -32.3±5.9%) (each p<0.001), while FT derived endocardial PSCS and tagging derived midmyocardial PSCS showed a strong correlation (r=0.71) and no significant differences. Global intra- and inter-observer variability of FT derived endocardial PSCS circumferential measures were acceptable (coefficient of variation 6.5% and 5.7%) while reproducibility of epicardial PSCS (coefficient of variation 16.8% and 18.1%) was poor.

CONCLUSION

The FT algorithm allows for reliable assessment of midmyocardial strain, while underestimating epicardial and endocardial strain and delivering less reproducible results than the gold standard of tagging.

摘要

目的

层特异性应变评估在临床上的应用越来越广泛。心脏磁共振（MR）特征追踪（FT）被认为是应变评估的一种合适替代方法。本研究旨在探讨 FT 衍生的层特异性应变评估的可行性。

方法

在 38 名个体（19 名射血分数保留型心力衰竭患者，19 名对照者）的相同中部心室短轴位置采集 CSPAMM 和 SSFP-Cine 序列。计算整体心内膜、心肌中层、心外膜-收缩期峰值周向应变（PSCS）和区域性心外膜 PSCS，并评估观察者内和观察者间的可变性。

结果

FT 衍生的整体心外膜和心内膜 PSCS（7.9±2.3%；-19.6±4.9%）明显低于标记衍生的整体心外膜和心内膜 PSCS（-13.2±2.8%；-32.3±5.9%）（均<0.001），而 FT 衍生的心内膜 PSCS 与标记衍生的心肌中层 PSCS 呈强相关性（r=0.71）且无显著差异。FT 衍生的心内膜 PSCS 周向测量的观察者内和观察者间的变异性均在可接受范围（变异系数为 6.5%和 5.7%），而心外膜 PSCS 的重现性较差（变异系数为 16.8%和 18.1%）。