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神经外科领域的肥胖问题:文献综述

Obesity in Neurosurgery: A Narrative Review of the Literature.

作者信息

Castle-Kirszbaum Mendel D, Tee Jin W, Chan Patrick, Hunn Martin K

机构信息

Department of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.

Department of Neurosurgery, Alfred Hospital, Melbourne, Victoria, Australia.

出版信息

World Neurosurg. 2017 Oct;106:790-805. doi: 10.1016/j.wneu.2017.06.049. Epub 2017 Jun 15.

Abstract

Obesity is an important consideration in neurosurgical practice. Of Australian adults, 28.3% are obese and it is estimated that more than two thirds of Australia's population will be overweight or obese by 2025. This review of the effects of obesity on neurosurgical procedures shows that, in patients undergoing spinal surgery, an increased body mass index is a significant risk factor for surgical site infection, venous thromboembolism, major medical complications, prolonged length of surgery, and increased financial cost. Although outcome scores and levels of patient satisfaction are generally lower after spinal surgery in obese patients, obesity is not a barrier to deriving benefit from surgery and, when the natural history of conservative management is taken into account, the long-term benefits of surgery may be equivalent or even greater in obese patients than in nonobese patients. In cranial surgery, the impact of obesity on outcome and complication rates is generally lower. Specific exceptions are higher rates of distal catheter migration after shunt surgery and cerebrospinal fluid leak after posterior fossa surgery. Minimally invasive approaches show promise in mitigating some of the adverse effects of obesity in patients undergoing spine surgery but further studies are needed to develop strategies to reduce obesity-related surgical complications.

摘要

肥胖是神经外科手术实践中的一个重要考量因素。在澳大利亚成年人中,28.3%为肥胖者,据估计到2025年澳大利亚超过三分之二的人口将超重或肥胖。这篇关于肥胖对神经外科手术影响的综述表明,在接受脊柱手术的患者中,体重指数增加是手术部位感染、静脉血栓栓塞、严重医疗并发症、手术时间延长和费用增加的重要危险因素。尽管肥胖患者脊柱手术后的结果评分和患者满意度通常较低,但肥胖并非从手术中获益的障碍,考虑到保守治疗的自然病程,肥胖患者手术的长期益处可能与非肥胖患者相当甚至更大。在颅脑手术中,肥胖对手术结果和并发症发生率的影响通常较小。具体的例外情况是分流手术后远端导管移位率较高以及后颅窝手术后脑脊液漏发生率较高。微创方法有望减轻肥胖对脊柱手术患者的一些不利影响,但需要进一步研究以制定减少肥胖相关手术并发症的策略。

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