Glatter M, Bochnia M, Goetz F, Gottschalk J, Koeller G, Mielenz N, Hillegeist D, Greef J M, Einspanier A, Zeyner A
Institute of Agricultural and Nutritional Sciences, Group Animal Nutrition, Martin Luther University Halle-Wittenberg, Halle/Saale, Germany.
Institute of Physiological Chemistry, Faculty of Veterinary Medicine, University of Leipzig, Leipzig, Germany.
J Anim Physiol Anim Nutr (Berl). 2017 Jun;101 Suppl 1:69-78. doi: 10.1111/jpn.12669.
This study aimed to investigate the impact of the supplementation of a pre-biotic compound [Jerusalem artichoke meal (JAM)] on the glycaemic and insulinaemic response in healthy, non-obese warm-blooded horses. Six adult mares [mean body weight (bwt) 529 ± 38.7 kg; body condition score 5.1 ± 0.49/9] were used. In two equal meals per day, the horses received crushed oat grains (1 g starch/kg bwt per day) and meadow hay (2 kg/100 kg bwt per day) which together were likely to meet the energy recommendation for light work (GfE, ). Additionally, they received either 0.15 g fructo-oligosaccharides and inulin (FOS+INU)/kg bwt per day via commercial JAM or maize cob meal without grains as control (CON) in 2 × 3-week periods according to a crossover design. Blood was collected on d21 of the feeding period at different ante- and postprandial (PP) time points (-60, 0, 30, 60, 90, 120, 180, 240 and 300 min), and the plasma glucose and serum insulin levels were determined. Feeding JAM vs. CON did not change the PP peak of glucose or insulin (glucose: 6.3 ± 0.40 vs. 7.0 ± 0.87 mmol/l; insulin: 0.508 ± 0.087 vs. 0.476 ± 0.082 nmol/l) nor did it cause different AUCs until 120 and 300 min PP for glucose and insulin, respectively (AUC , glucose: 997 ± 41.6 vs. 1015 ± 41.63 mmol/l per minute, insulin: 49 ± 6.3 vs. 42 ± 6.3 nmol/l per minute; AUC , glucose: 1943 ± 142.3 vs. 2115 ± 142.3 mmol/l per minute, insulin: 94 ± 14.8 vs. 106 ± 14.8 nmol/l per minute; p > 0.05). Following JAM vs. CON feeding, glucose and insulin levels declined more rapidly until 240 min PP and tended to be lower (p = 0.053 and p = 0.056, respectively) at this time point. This result might be promising and should further be studied more detailed.
本研究旨在调查补充益生元化合物[菊芋粉（JAM）]对健康、非肥胖温血马的血糖和胰岛素反应的影响。使用了6匹成年母马[平均体重（bwt）529±38.7千克；身体状况评分为5.1±0.49/9]。马匹每天分两顿等量进食，摄入碾碎的燕麦粒（每天1克淀粉/千克体重）和草地干草（每天2千克/100千克体重），这些食物合在一起可能满足轻度工作的能量推荐量（GfE）。此外，根据交叉设计，在两个3周的时间段内，它们每天每千克体重分别通过商业菊芋粉接受0.15克低聚果糖和菊粉（FOS+INU），或接受不含谷物的玉米芯粉作为对照（CON）。在喂食期的第21天，于不同的餐前和餐后（PP）时间点（-60、0、30、60、90、120、180、240和300分钟）采集血液，测定血浆葡萄糖和血清胰岛素水平。喂食菊芋粉与对照组相比，并未改变葡萄糖或胰岛素的餐后峰值（葡萄糖：6.3±0.40对7.0±0.87毫摩尔/升；胰岛素：0.508±0.087对0.476±0.082纳摩尔/升），在餐后120分钟和300分钟时，葡萄糖和胰岛素的曲线下面积（AUC）也没有差异（AUC，葡萄糖：997±41.6对1015±41.63毫摩尔/升·分钟，胰岛素：49±6.3对42±6.3纳摩尔/升·分钟；AUC，葡萄糖：1943±142.3对2115±142.3毫摩尔/升·分钟，胰岛素：94±14.8对106±14.8纳摩尔/升·分钟；p>0.05）。与喂食对照组相比，喂食菊芋粉后，直到餐后240分钟，葡萄糖和胰岛素水平下降得更快，且在该时间点趋于更低（分别为p=0.053和p=0.056）。这一结果可能很有前景，应进一步进行更详细的研究。
