Vagin Iu E, Shurygina A P, Batsiuro S G
Zh Vyssh Nerv Deiat Im I P Pavlova. 1985 Mar-Apr;35(2):322-9.
33 acetylcholine perfusions were carried out on 14 neurones RPal of a snail, 25 serotonin perfusions on 15 neurones, and 10 dopamine perfusions on 12 neurones. Frequency of unit activity (FUA) was analysed as well as its irregularity (IUA). The latter was calculated by a new method of successive comparison of the lengths of interspike intervals which accounts more adequately for causes of lengthening of each interval in comparison to evaluation of dispersion and coefficient of variation. During the neurotransmitters' action, IUA did not depend on the background IUA and the duration of its return to the background level from the moment of the beginning of neurotransmitter action. At low neurotransmitter concentrations, FUA changed less than by 0.5 spike/s. IUA assumed any values from 8 to 68 per cent and lasted for different periods from 22 to 448 s depending on the kind of neurotransmitter. At high neurotransmitter concentrations, FUA changed more than by 1 spike/s. IUA took only high values from 33 to 80 per cent and lasted only from 18 to 62 s. The value of IUA reflects the tension of neuronal processes directed to preservation of stable rhythmical activity.
对一只蜗牛的14个RPal神经元进行了33次乙酰胆碱灌注，对15个神经元进行了25次血清素灌注，对12个神经元进行了10次多巴胺灌注。分析了单位活动频率（FUA）及其不规则性（IUA）。后者是通过一种新的连续比较峰间间隔长度的方法计算得出的，与评估离散度和变异系数相比，该方法更充分地考虑了每个间隔延长的原因。在神经递质作用期间，IUA不依赖于背景IUA及其从神经递质作用开始时刻恢复到背景水平的持续时间。在低神经递质浓度下，FUA变化小于0.5个峰/秒。IUA取值范围为8%至68%，持续时间从22秒到448秒不等，具体取决于神经递质的种类。在高神经递质浓度下，FUA变化超过1个峰/秒。IUA仅取33%至80%的高值，持续时间仅为18秒至62秒。IUA的值反映了旨在维持稳定节律活动的神经元过程的紧张程度。
