美沙酮加抗精神病药对难治性慢性偏执型精神分裂症的疗效
Effect of methadone plus neuroleptics on treatment-resistant chronic paranoid schizophrenia.
作者信息
Brizer D A, Hartman N, Sweeney J, Millman R B
出版信息
Am J Psychiatry. 1985 Sep;142(9):1106-7. doi: 10.1176/ajp.142.9.1106.
PMID:2862800
Abstract
In a placebo-controlled single-crossover study, seven patients with treatment-resistant chronic paranoid schizophrenia who received methadone plus neuroleptic showed significant improvement. Methadone may be a useful adjunctive treatment in a subpopulation of patients with chronic paranoid schizophrenia.
摘要
在一项安慰剂对照的单交叉研究中，7例接受美沙酮加抗精神病药物治疗的难治性慢性偏执型精神分裂症患者病情有显著改善。美沙酮可能是慢性偏执型精神分裂症患者亚群中一种有用的辅助治疗方法。
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