Portier A, Sarfati Y
Centre hospitalier Victor Dupouy, Argenteuil.
Encephale. 2000 Jul-Aug;26(4):75-7.
Ms M is a young female patient (born 1968) with paranoid schizophrenia. The first acute psychotic episode, which involved marked delirium, was treated with an atypical antipsychotic agent. During the next year, renewed hospitalisation and treatment with two other antipsychotics resulted only in partial improvement, and troublesome adverse effects were noted. Amelioration of all symptoms, both psychotic and debilitating, was finally obtained through prescription of a third atypical antipsychotic with which the patient was highly satisfied. We examine the value of first-line treatment of schizophrenia with atypical antipsychotics as of the first acute episodes of acute delirium in the light of current data in the literature.
M女士是一名患有偏执型精神分裂症的年轻女性患者（生于1968年）。她的首次急性精神病发作伴有明显的谵妄，使用非典型抗精神病药物进行了治疗。在接下来的一年里，再次住院并使用另外两种抗精神病药物治疗，仅取得了部分改善，且出现了令人困扰的不良反应。最终，通过开具第三种非典型抗精神病药物，患者所有的精神病性症状和衰弱症状都得到了改善，患者对此高度满意。我们根据文献中的现有数据，探讨在急性谵妄的首次急性发作时，使用非典型抗精神病药物作为精神分裂症一线治疗的价值。
