Zamora Salas Juan Diego, Laclé-Murray Adriana
Instituto de Investigación en Salud (INISA), Universidad de Costa Rica, San José, Costa Rica, América Central.
Am J Hum Biol. 2017 Sep 10;29(5). doi: 10.1002/ajhb.23028. Epub 2017 Jun 19.
The purpose of this study was to verify the validity of body fat percentage (BF%) by bioelectrical impedance analysis (BIA) in a sample of Costa Rican schoolchildren.
The sample consisted of 52 male (mean age 8.1 ± 0.9 years) and 49 female (mean age 7.5 ± 1.0 years) schoolchildren. Deuterium oxide dilution was the reference method used as the "gold standard" to determine the fat mass (FM) expressed as BF%. Linear regression analyses and paired sample t-tests were used to test the association and mean differences between BIA and deuterium oxide dilution BF%. Concordance between BIA and deuterium oxide dilution BF% was determined by Lin's concordance correlation coefficient. Measurement of agreement between the two methods was analyzed using the Bland-Altman procedure.
Significant associations between BIA and deuterium oxide dilution BF% were found in males (R = 0.97, R = 0.95, P < .0001) and in females (R = 0.98, R = .96, P < .0001). The measurements of BF% (mean ± SD) were not significantly different between males (BIA 31.1 ± 7.6% vs. deuterium oxide dilution 31.0 ± 7.4%) and females (BIA 25.9 ± 7.9% vs. deuterium oxide dilution 26.3 ± 7.8%) by t-test. Lin's concordance correlation coefficient identified an almost perfect strength of agreement between males and females. Bland-Altman plots showed that the Bodystat measured similar BF% compared to the deuterium oxide dilution in both males and females.
BIA Bodystat presented high agreement with BF% measured by deuterium oxide dilution; therefore BIA Bodystat is recommended for estimating BF% in Costa Rican schoolchildren.
本研究旨在验证生物电阻抗分析(BIA)法测定哥斯达黎加学龄儿童体脂百分比(BF%)的有效性。
样本包括52名男性(平均年龄8.1±0.9岁)和49名女性(平均年龄7.5±1.0岁)学龄儿童。以氧化氘稀释法作为“金标准”参考方法来测定以BF%表示的脂肪量(FM)。采用线性回归分析和配对样本t检验来检验BIA法与氧化氘稀释法测定BF%之间的相关性及均值差异。通过林氏一致性相关系数来确定BIA法与氧化氘稀释法测定BF%之间的一致性。使用布兰德-奥特曼法分析两种方法之间的测量一致性。
在男性(R = 0.97,R² = 0.95,P <.0001)和女性(R = 0.98,R² =.96,P <.0001)中均发现BIA法与氧化氘稀释法测定BF%之间存在显著相关性。通过t检验可知,男性(BIA法测定值为31.1±7.6%,氧化氘稀释法测定值为31.0±7.4%)和女性(BIA法测定值为25.9±7.9%,氧化氘稀释法测定值为26.3±7.8%)的BF%测量值无显著差异。林氏一致性相关系数表明男性和女性之间的一致性强度近乎完美。布兰德-奥特曼图显示,与氧化氘稀释法相比,Bodystat生物电阻抗分析仪在男性和女性中测量的BF%相似。
BIA法Bodystat生物电阻抗分析仪与氧化氘稀释法测定的BF%高度一致;因此,推荐使用BIA法Bodystat生物电阻抗分析仪来估算哥斯达黎加学龄儿童的BF%。