雄激素和促性腺激素对鸡颗粒细胞孕酮分泌的影响。
Effect of androgens and gonadotropins on progesterone secretion of chicken granulosa cells.
作者信息
Phillips A, Scanes C G, Hahn D W
出版信息
Comp Biochem Physiol A Comp Physiol. 1985;81(4):847-52. doi: 10.1016/0300-9629(85)90917-x.
A culture system has been used to study the effect of PMSG in vivo pretreatment and androgens on the in vitro secretion of progesterone from avian granulosa cells. PMSG in vivo pretreated cells secreted greater amounts of progesterone than did cells obtained from untreated hens. Testosterone and 5-alpha-dihydrotestosterone significantly increased basal progesterone secretion in PMSG pretreated cells as well as in granulosa cells harvested from non-treated hens. Testosterone or 5 alpha-dihydrotestosterone in combination with FSH or LH were additive and never resulted in a synergistic stimulation of progesterone secretion.
一种培养系统已被用于研究孕马血清促性腺激素（PMSG）体内预处理及雄激素对禽类颗粒细胞体外分泌孕酮的影响。经PMSG体内预处理的细胞比从未经处理母鸡获得的细胞分泌更多的孕酮。睾酮和5-α-二氢睾酮显著增加了经PMSG预处理细胞以及从未经处理母鸡收获的颗粒细胞的基础孕酮分泌。睾酮或5-α-二氢睾酮与促卵泡激素（FSH）或促黄体生成素（LH）联合使用具有相加作用，且从未导致对孕酮分泌的协同刺激。
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