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醒脑舒口服液治疗脑出血的系统评价和荟萃分析。

A Systematic Review and Meta-Analysis on the Treatment of Cerebral Hemorrhage with NaoXueShu Oral Liquid.

机构信息

Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Key Office of Encephalopathy TCM Research, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China.

Weishi Hospital of Traditional Chinese Medicine, Henan 475500, China.

出版信息

Biomed Res Int. 2017;2017:8542576. doi: 10.1155/2017/8542576. Epub 2017 May 29.

DOI:10.1155/2017/8542576
PMID:28630871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5467282/
Abstract

NaoXueShu oral liquid invigorates Qi and promotes blood circulation, which is mainly used for treating the acute stage of the meridian of hemorrhagic apoplexy and acute blood stasis syndrome during early convalescence. Its main clinical manifestations include hemiplegia, mouth askew, hemianesthesia, and inarticulateness. It is used mainly in patients with lobar hemorrhage, basal ganglia, and thalamus of the small amount of bleeding without disturbing consciousness of hypertensive cerebral. The purpose of this study was to evaluate the efficacy and adverse effects of NaoXueShu oral liquid on the treatment of cerebral hemorrhage. In this study, literature on randomized controlled trials was collected from seven databases to evaluate the clinical efficiency of the treatment of cerebral hemorrhage alone or combined with Western medicine. The methodologic quality of the included studies was assessed using a standard Cochrane system review and analyzed using RevMan 5.3.0 software. The study included 14 eligible randomized controlled trials. The results showed that the use of NaoXueShu oral liquid alone or combined with other drugs or auxiliary methods can play a significant role in the treatment of cerebral hemorrhage, especially hypertensive intracerebral hemorrhage.

摘要

脑血疏口服液具有益气活血的功效,主要用于治疗出血性中风急性期和瘀血阻络恢复期,其主要临床症状为半身不遂、口角歪斜、偏身麻木、言语不利等。主要适用于高血压性脑出血少量出血且不伴有意识障碍者的脑内病灶。本研究旨在评价脑血疏口服液治疗脑出血的有效性和安全性。本研究通过对七个数据库中的随机对照试验文献进行收集,评价单纯应用或联合西药治疗脑出血的临床疗效。采用 Cochrane 系统评价方法学质量标准对纳入的研究进行评价,并运用 RevMan 5.3.0 软件进行分析。本研究共纳入 14 项随机对照试验。结果显示,脑血疏口服液单独应用或联合其他药物或辅助方法治疗脑出血,尤其是高血压性脑出血,均能发挥显著作用。

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Nao-Xue-Shu Oral Liquid Protects and Improves Secondary Brain Insults of Hypertensive Cerebral Hemorrhage.
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