Sali Akash, Epari Sridhar, Tampi Chandralekha, Goel Atul
Department of Pathology, Tata Memorial Hospital and ACTREC, Tata Memorial Centre, Mumbai, India.
Lilavati Hospital and Research Centre, Mumbai, India.
Neuropathology. 2017 Dec;37(6):535-543. doi: 10.1111/neup.12393. Epub 2017 Jun 19.
Spindle cell oncocytoma (SCO) of adenohypophysis was first described in 2002 by Roncaroli et al. as a new entity in the tumors originating from adenohypophysis. It was subsequently recognized as a distinct entity in the 2007 WHO classification of CNS tumors and retained in the current updated classification. In contrast to that suggested by the original authors, this tumor does have a potential for recurrence as first described by Kloub et al. and later with many such case reports. This tumor can be confused with other sellar tumors like pituicytomas and pituitary adenoma, both radiologically and histopathologically. However, it is imperative to differentiate these tumors from the above-mentioned differential diagnoses as it certainly has a recurrent potential. To date only 34 cases of SCO have been published in the English literature. Herein we present a rare SCO case with unusually aggressive course in a 64-year-old man, which recurred 4 years after the initial diagnosis.
腺垂体的梭形细胞嗜酸细胞瘤(SCO)于2002年由Roncaroli等人首次描述,是起源于腺垂体的肿瘤中的一种新实体。随后,它在2007年世界卫生组织中枢神经系统肿瘤分类中被确认为一个独特的实体,并保留在当前的更新分类中。与最初作者的观点相反,正如Kloub等人首先描述的以及后来许多此类病例报告所示,这种肿瘤确实有复发的可能性。该肿瘤在放射学和组织病理学上都可能与其他鞍区肿瘤如垂体细胞瘤和垂体腺瘤相混淆。然而,必须将这些肿瘤与上述鉴别诊断区分开来,因为它确实具有复发潜力。迄今为止,英文文献中仅发表了34例SCO病例。在此,我们报告一例罕见的SCO病例,该病例发生在一名64岁男性身上,病程异常侵袭性,在初次诊断4年后复发。