Department of Chemistry and Chemical Engineering, Inha University , 100 Inha-ro, Nam-gu, Incheon 402-751, Korea.
Department Molecular Imaging Research Center, Korea Institute of Radiological and Medical Sciences , 75 Nowon-ro, Nowon-gu, Seoul 139-706, Korea.
Org Lett. 2017 Jul 7;19(13):3342-3345. doi: 10.1021/acs.orglett.7b01064. Epub 2017 Jun 20.
We prepared pyrene-substituted imidazolium-based ionic liquids (PILs) as organic catalysts for the S2 fluorination using alkali metal fluoride (MF). In this system, the PIL significantly enhanced the reactivity of MF due to the phase-transfer catalytic effect of the imidazolium moiety as well as the metal cation-π (pyrene) interactions. Furthermore, this homogeneous catalyst PIL was easily separated from the reaction mixture using reduced graphene oxide by π-π stacking with the pyrene of PIL.
我们制备了芘取代的咪唑基离子液体（PILs）作为有机催化剂，用于使用碱金属氟化物（MF）的 S2 氟化反应。在该体系中，PIL 通过咪唑部分的相转移催化作用以及金属阳离子-π（芘）相互作用，显著提高了 MF 的反应活性。此外，通过 PIL 的芘与还原氧化石墨烯之间的π-π堆积，这种均相催化剂 PIL 可以很容易地从反应混合物中分离出来。
