Block Katherine, Battig Jean
1 Animal Dental Clinic NW, Lake Oswego, OR, USA.
J Vet Dent. 2017 Jun;34(2):76-85. doi: 10.1177/0898756417714025.
An 18-month-old neutered male labradoodle was treated with surgical debridement for maxillary osteomyelitis and sequestrum formation. Histopathologic findings of the necrotic bone were consistent with Cryptococcus subspecies, confirmed with latex agglutination serum titer testing. The patient responded to a combination of fluconazole and surgical debridement and was titer negative after 8 months of medical therapy. The patient never exhibited signs of systemic illness which is commonly reported with cryptococcosis. Cryptococcus subspecies infection in dogs in the Pacific Northwest is part of an ongoing outbreak in the region, first reported in 2001, and is associated with specific risk factors. This is the first published case of oral cryptococcosis from primary inoculation.
一只18个月大的绝育雄性拉布拉多贵宾犬因上颌骨髓炎和死骨形成接受了手术清创治疗。坏死骨的组织病理学检查结果与隐球菌亚种一致，乳胶凝集血清滴度检测予以证实。该患者对氟康唑和手术清创的联合治疗有反应，药物治疗8个月后滴度转阴。该患者从未表现出通常与隐球菌病相关的全身疾病症状。太平洋西北部地区犬类的隐球菌亚种感染是该地区自2001年首次报告以来持续爆发疫情的一部分，且与特定风险因素相关。这是首例关于原发性接种引起口腔隐球菌病的病例报道。
