Pamukcu Ozge, Narin Nazmi, Baykan Ali, Sunkak Suleyman, Tasci Onur, Uzum Kazim
Division of Pediatric Cardiology,Erciyes University School of Medicine,Kayseri,Turkey.
Cardiol Young. 2017 Nov;27(9):1726-1731. doi: 10.1017/S104795111700107X. Epub 2017 Jun 20.
Aim The aim of this study was to share the mid-term results of percutaneous ventricular septal defect closure using Amplatzer Duct Occluder-II in children.
Nowadays, percutaneous ventricular septal defect closure is accepted as an alternative to surgery, but so far no ideal device has been developed for this procedure.
In the study centre, between April, 2011 and October, 2016, the ventricular septal defect of 49 patients was closed percutaneously using the Amplatzer Duct Occluder-II device, and seven of them were <1 year old.
The mean age of patients was 86.8±52.6 months. The mean weight of the patients was 24.3±16 kg. The mean diameter of the defect was 3.7±1.4 mm. Mean fluoroscopy time and total procedure time were 37±19.3 and 74.1±27 minutes, respectively. The types of ventricular septal defects were muscular in six patients, and were perimembranous in the rest of them. We did not face any major complications during the procedure, but one patient was admitted with a complete atrioventricular block in the 6th month of follow-up. The total follow-up period was 66 months.
To our knowledge, our study includes the largest series of paediatric patients whose ventricular septal defect was closed using Amplatzer Duct Occluder-II percutaneously. When the complications during the 66-month follow-up period are taken into consideration, we can state that Amplatzer Duct Occluder-II is a safe and effective device, even in infants aged <1 year.
目的 本研究的目的是分享使用Amplatzer II型动脉导管封堵器经皮闭合儿童室间隔缺损的中期结果。
如今，经皮闭合室间隔缺损已被公认为手术的替代方法，但迄今为止尚未开发出用于该手术的理想装置。
在研究中心，2011年4月至2016年10月期间，使用Amplatzer II型动脉导管封堵器经皮闭合了49例患者的室间隔缺损，其中7例年龄小于1岁。
患者的平均年龄为86.8±52.6个月。患者的平均体重为24.3±16千克。缺损的平均直径为3.7±1.4毫米。平均透视时间和总手术时间分别为37±19.3分钟和74.1±27分钟。室间隔缺损类型为肌部的有6例，其余为膜周部。手术过程中未出现任何严重并发症，但1例患者在随访第6个月时出现完全性房室传导阻滞。总随访期为66个月。
据我们所知，我们的研究纳入了使用Amplatzer II型动脉导管封堵器经皮闭合室间隔缺损的最大系列儿科患者。考虑到66个月随访期内的并发症情况，我们可以说Amplatzer II型动脉导管封堵器是一种安全有效的装置，即使对于年龄小于1岁的婴儿也是如此。
