Lowenthal Brett Matthew, Xu Xiangdong, Subash Meera, Jih Lily J
Department of Pathology, University of California, 9500 Gilman Drive, La Jolla, San Diego, CA, USA.
Department of Pathology, University of California, 9500 Gilman Drive; Department of Pathology, Veteran Administration Medical Center, 3350 La Jolla Village Drive (113), La Jolla, San Diego, CA, USA.
Indian J Pathol Microbiol. 2017 Apr-Jun;60(2):272-274. doi: 10.4103/IJPM.IJPM_687_16.
Classical Hodgkin's lymphoma (CHL) presenting with exclusively pulmonary symptoms is very unusual. We report two cases of CHL with atypical clinical presentations mimicking pulmonary infections. The first case represents a stage IV CHL with secondary lung involvement, and the second case demonstrates a very rare case of CHL with isolated lung involvement, also known as primary pulmonary Hodgkin's lymphoma. The second patient was initially misdiagnosed and treated with six months of antibiotics before the correct diagnosis was made by a lung biopsy. Both patients received chemotherapy; one patient achieved complete remission and the other achieved near-complete remission.
仅表现为肺部症状的经典型霍奇金淋巴瘤（CHL）非常罕见。我们报告两例具有非典型临床表现、酷似肺部感染的CHL病例。第一例为伴有继发性肺部受累的IV期CHL，第二例为非常罕见的孤立性肺部受累的CHL病例，也称为原发性肺霍奇金淋巴瘤。第二例患者最初被误诊，并接受了六个月的抗生素治疗，之后通过肺活检才做出正确诊断。两名患者均接受了化疗；一名患者实现了完全缓解，另一名患者实现了接近完全缓解。
