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快速进展性痴呆:一个不寻常的病因。

Rapidly progressive dementia: an unusual cause.

作者信息

Takkar Aastha, Singla Veenu, Modi Manish, Gupta Vivek, Goyal Manoj K, Lal Vivek

机构信息

1 Department of Neurology, Post Graduate Institute of Medical Education and Research, India.

2 Department of Radiology, Post Graduate Institute of Medical Education and Research, India.

出版信息

Neuroradiol J. 2017 Aug;30(4):336-338. doi: 10.1177/1971400917706083. Epub 2017 Jun 20.

DOI:10.1177/1971400917706083
PMID:28631971
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5524276/
Abstract

Brain metastases are known to be present with a history of increased intra-cranial pressure headache, seizures or altered sensorium. Corresponding to the clinical brain metastases are the most feared complication of a systemic cancer. Classically, brain metastases are associated with significant morbidity and are known to present with a history of increased intracranial pressure headache, seizures or altered sensorium. Neuroimaging is usually suggestive of massive peri-lesional edema and mass effect surrounding the space occupying lesions. This, however it is not a universal rule. We report a 50-year-old gentleman who presented with rapidly progressive forgetfulness. Interestingly, the patient's neuroimaging discretely showed disproportionate involvement with regards to the clinical picture. The lesions were finally recognized as metastases underscoring the importance of an avid search for a primary systemic malignancy if similar findings are noted on radiology.

摘要

已知脑转移瘤会伴有颅内压增高性头痛、癫痫发作或意识改变的病史。与临床脑转移瘤相对应的是系统性癌症最可怕的并发症。传统上,脑转移瘤与严重的发病率相关,并且已知会伴有颅内压增高性头痛、癫痫发作或意识改变的病史。神经影像学通常提示占位性病变周围有大量的瘤周水肿和占位效应。然而,这并非普遍规律。我们报告了一位50岁的男性患者,他表现为快速进展的遗忘症。有趣的是,患者的神经影像学检查结果与临床表现明显不符。这些病变最终被确认为转移瘤,强调了如果在放射学检查中发现类似结果,积极寻找原发性系统性恶性肿瘤的重要性。

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本文引用的文献

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Rapidly Progressive Dementia.快速进展性痴呆
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METASTATIC NEOPLASMS OF THE BRAIN: THEIR FREQUENCY IN RELATION TO AGE.脑转移性肿瘤:其发病率与年龄的关系
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