Zheng Kang Keng, Cai Jianhao, Rong Shi Song, Peng Kun, Xia Honghe, Jin Chuan, Lu Xuehui, Liu Xinyu, Chen Haoyu, Jhanji Vishal
a Joint Shantou International Eye Center , Shantou University and the Chinese University of Hong Kong, Shantou , Guangdong Province , China.
b Department of Ophthalmology and Visual Sciences , The Chinese University of Hong Kong , Hong Kong.
Curr Eye Res. 2017 Jul;42(7):982-986. doi: 10.1080/02713683.2016.1274038. Epub 2017 Feb 26.
Ocular imaging can enhance our understanding of wound healing. We report anterior segment optical coherence tomography (ASOCT) findings in penetrating corneal injury.
Serial ASOCT was performed after repair of penetrating corneal injury. Internal aberrations of wound edges were labeled as "steps" or "gaps" on ASOCT images. The wound type was characterized as: type 1: continuous inner wound edge or step height ≤ 80 µm; type 2: step height > 80 µm; type 3: gap between wound edges; and type 4: intraocular tissue adherent to wound. Surgical outcomes of different wound types were compared.
50 consecutive patients were included (6 females, 44 males; mean age 33 ± 12 years). The average size of wound was 4.2 ± 2.6 mm (type 1, 8 eyes; type 2, 27 eyes; type 3, 12 eyes; type 4, 3 eyes). At the end of 3 months, 70% (n = 35) of the wounds were type 1. At the end of 6 months, all type 1 wounds had healed completely, whereas about half of type 2 (48.1%) and type 3 (50%) wounds had recovered to type 1 configuration. The wound type at baseline affected the height of step (p = 0.047) and corneal thickness at 6 months (p = 0.035).
ASOCT is a useful tool for monitoring wound healing in cases with penetrating corneal injury. Majority of the wound edges appose between 3 and 6 months after trauma. In our study, baseline wound configuration affected the healing pattern.
眼部成像可增强我们对伤口愈合的理解。我们报告穿透性角膜损伤的眼前节光学相干断层扫描（ASOCT）结果。
穿透性角膜损伤修复后进行系列ASOCT检查。在ASOCT图像上，伤口边缘的内部像差标记为“台阶”或“间隙”。伤口类型分为：1型：内伤口边缘连续或台阶高度≤80 µm；2型：台阶高度>80 µm；3型：伤口边缘之间有间隙；4型：眼内组织附着于伤口。比较不同伤口类型的手术结果。
纳入50例连续患者（女性6例，男性44例；平均年龄33±12岁）。伤口平均大小为4.2±2.6 mm（1型8眼；2型27眼；3型12眼；4型3眼）。3个月末，70%（n = 35）的伤口为1型。6个月末，所有1型伤口完全愈合，而约一半的2型（48.1%）和3型（50%）伤口恢复为1型形态。基线时的伤口类型影响台阶高度（p = 0.047）和6个月时的角膜厚度（p = 0.035）。
ASOCT是监测穿透性角膜损伤病例伤口愈合的有用工具。创伤后3至6个月，大多数伤口边缘对合。在我们的研究中，基线伤口形态影响愈合模式。
