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与弓形虫病和获得性免疫缺陷综合征相关的广泛脑肿块和空洞性肺部病变。

Extensive brain masses and cavitary lung lesions associated with toxoplasmosis and acquired immunodeficiency syndrome.

作者信息

Ayoade Folusakin, Todd John, Al-Delfi Firas, King John

机构信息

Louisiana State University Health Sciences Center, Shreveport, LA, USA.

出版信息

Int J STD AIDS. 2017 Oct;28(11):1150-1154. doi: 10.1177/0956462417696216. Epub 2017 Mar 2.

DOI:10.1177/0956462417696216
PMID:28632476
Abstract

Toxoplasmosis is an important cause of enhancing brain lesions in patients with acquired immunodeficiency syndrome (AIDS), and it is typically associated with low CD4-lymphocyte counts. Extensive toxoplasma encephalitis when the CD4-lymphocyte count is above 100 cells/µl is unusual. Cavitary lung lesions are also not typically associated with toxoplasmosis. Here, we present a case of toxoplasmosis associated with extensive brain masses and cavitary lung lesions, both of which improved with directed toxoplasmosis therapy, in an AIDS patient with a CD4 cell count of 120 cells/µl.

摘要

弓形虫病是获得性免疫缺陷综合征(AIDS)患者脑部强化病变的重要原因,通常与CD4淋巴细胞计数低有关。CD4淋巴细胞计数高于100个细胞/微升时发生广泛的弓形虫脑炎并不常见。空洞性肺部病变通常也与弓形虫病无关。在此,我们报告一例艾滋病患者,其CD4细胞计数为120个细胞/微升,患有与广泛脑肿块和空洞性肺部病变相关的弓形虫病,经针对性弓形虫病治疗后二者均有所改善。

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