Desai Dimpi, Rao Devika, Sukrithan Vineeth, Weinstein Eleanor, Goyal Akankasha, Schubart Ulrich
Jacobi Medical Center, Bronx, NY, USA.
Montefiore Hospital and Medical Center, Bronx, NY, USA.
J Investig Med High Impact Case Rep. 2017 Jun 8;5(2):2324709617714286. doi: 10.1177/2324709617714286. eCollection 2017 Apr-Jun.
Pancreatic ductal adenocarcinoma is the third leading cause of cancer-related death in the United States. Since it is usually diagnosed at an advanced stage, its prognosis remains poor. The initial presentation varies according to the tumor location. The most common presenting signs are weight loss, jaundice, and pain. Several epidemiological, clinical, and experimental studies over the past 2 decades have shown that long-standing diabetes is a modest risk factor for pancreatic cancer. However, new-onset diabetes has also been observed to be an early manifestation of pancreatic cancer. We report 2 cases where worsening glycemic control led to the diagnosis of pancreatic cancer.
胰腺导管腺癌是美国癌症相关死亡的第三大主要原因。由于它通常在晚期才被诊断出来，其预后仍然很差。最初的表现因肿瘤位置而异。最常见的症状是体重减轻、黄疸和疼痛。过去20年的几项流行病学、临床和实验研究表明，长期糖尿病是胰腺癌的一个适度风险因素。然而，也观察到新发糖尿病是胰腺癌的早期表现。我们报告2例血糖控制恶化导致胰腺癌诊断的病例。
