Department of Medicine, University of Alberta, Edmonton, Canada.
Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
J Hum Nutr Diet. 2017 Dec;30(6):714-723. doi: 10.1111/jhn.12480. Epub 2017 Jun 20.
Little is known about the effects of carbohydrate, particularly any association between dietary glycaemic index or glycaemic load and uninvestigated heartburn or uninvestigated chronic dyspepsia in the community. The present study aimed to determine associations between dietary glycaemic index or glycaemic load and uninvestigated heartburn or uninvestigated chronic dyspepsia.
This cross-sectional study was conducted in 2987 adults. Dietary glycaemic index and glycaemic load were estimated using a validated food-frequency questionnaire. Uninvestigated heartburn and uninvestigated chronic dyspepsia were determined using a modified and validated version of the Rome III questionnaire.
After controlling for various confounders, high glycaemic load was associated with an increased risk of uninvestigated heartburn [odds ration (OR) = 1.75; 95% confidence interval CI = 1.03, 2.97; P = 0.04] and uninvestigated chronic dyspepsia (OR = 2.14; 95% CI: 1.04, 4.37; P = 0.04) in men but not in women. In normal-weight individuals, high glycaemic index was related to an increased risk of uninvestigated heartburn (OR = 1.52; 95% CI: 1.07, 2.15; P = 0.02) and high glycaemic load to an increased risk of uninvestigated chronic dyspepsia (OR=1.78; 95% CI: 1.05, 3.01; P = 0.03). No significant associations were observed in subjects with excess body weight.
Our data suggest that there are body mass index- and sex-specific associations between dietary carbohydrate quality with uninvestigated heartburn and uninvestigated chronic dyspepsia.
人们对碳水化合物的影响知之甚少，特别是饮食血糖指数或血糖负荷与社区中未经调查的胃灼热或未经调查的慢性消化不良之间的任何关联。本研究旨在确定饮食血糖指数或血糖负荷与未经调查的胃灼热或未经调查的慢性消化不良之间的关联。
本横断面研究纳入了 2987 名成年人。使用经过验证的食物频率问卷估计饮食血糖指数和血糖负荷。未经调查的胃灼热和未经调查的慢性消化不良使用罗马 III 问卷的改良和验证版本来确定。
在控制了各种混杂因素后，高血糖负荷与男性未经调查的胃灼热（比值比[OR] = 1.75；95%置信区间[CI] = 1.03，2.97；P = 0.04）和未经调查的慢性消化不良（OR = 2.14；95% CI：1.04，4.37；P = 0.04）风险增加相关，但在女性中则不然。在正常体重个体中，高血糖指数与未经调查的胃灼热风险增加相关（OR = 1.52；95% CI：1.07，2.15；P = 0.02），高血糖负荷与未经调查的慢性消化不良风险增加相关（OR = 1.78；95% CI：1.05，3.01；P = 0.03）。在超重个体中未观察到显著相关性。
我们的数据表明，饮食碳水化合物质量与未经调查的胃灼热和未经调查的慢性消化不良之间存在与体重指数和性别相关的关联。
