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重症监护后转入病房患者的意志康复评估:一项可行性研究。

Volitional rehabilitative assessments in patients admitted in a post-intensive care step down unit. A feasibility study.

作者信息

Paneroni Mara, D' Abrosca Francesco, Fokom Georges, Comini Laura, Vitacca Michele

机构信息

Respiratory Rehabilitation Division Fondazione Salvatore Maugeri, IRCCS Lumezzane (Brescia) - Italy.

出版信息

Monaldi Arch Chest Dis. 2017 May 18;87(1):764. doi: 10.4081/monaldi.2017.764.

Abstract

A high variability in functional tests and activities used during the pulmonary rehabilitation has been observed in post-intensive care unit (ICU) patients, and the best battery of tests to adopt has not been described yet. We tested in patients admitted in a post-ICU Step Down Unit the ability to perform the more frequent functional volitional tests. The relations of each single volitional test with general disability and dyspnea at discharge were also evaluated. Ten volitional tests including: bedside spirometry test (ST: FEV1%, FVC%), maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), Peak Expiratory Flow during Cough (PCEF), Quadriceps Muscle Strength (QMS), latissimus Dorsi and teres Major Strength (DMS), Brachial biceps Muscle Strength (BMS), effort tolerance measured by sit-to-stand test, Takahashi test and 6-Min Walking Test (6MWT), were evaluated in post-ICU patients at entry and discharge from in-hospital rehabilitation. General disability was assessed by Barthel Index, while dyspnea by Borg scale. At admission, >70% of subjects performed muscle strength test, while <25% performed respiratory and effort tolerance tests. At discharge, feasibility of spirometry, respiratory muscle strength and effort tolerance tests improved (all, p<0.001); 6MWT was the least feasible. At discharge, cardiorespiratory patients were more capable to perform tests compared to neurological ones. All outcome measures, with exception of FEV1%, and FVC%, were significantly related to the disability score. Peripheral muscle exercises showed the highest feasibility, spirometry and leg effort tolerance the lowest. Motor disability was explained mainly by the peripheral muscle strength. The study of non-volitional outcome measures and tests linked to a protocol-driven intervention should be performed in this specific population.

摘要

在重症监护病房(ICU)后的患者中,已观察到肺康复期间使用的功能测试和活动存在很大差异,并且尚未描述应采用的最佳测试组合。我们在ICU后降级病房收治的患者中测试了进行更频繁的功能性自主测试的能力。还评估了每项自主测试与出院时总体残疾和呼吸困难之间的关系。评估了十项自主测试,包括:床边肺活量测定试验(ST:第1秒用力呼气容积百分比、用力肺活量百分比)、最大吸气压力(MIP)、最大呼气压力(MEP)、咳嗽时的呼气峰值流量(PCEF)、股四头肌力量(QMS)、背阔肌和大圆肌力量(DMS)、肱二头肌力量(BMS)、通过坐立试验、高桥试验和6分钟步行试验(6MWT)测量的耐力,对ICU后患者入院时和出院时的院内康复情况进行评估。通过Barthel指数评估总体残疾情况,通过Borg量表评估呼吸困难情况。入院时,超过70%的受试者进行了肌肉力量测试,而进行呼吸和耐力测试的受试者不到25%。出院时,肺活量测定、呼吸肌力量和耐力测试的可行性有所提高(所有p<0.001);6MWT是最不可行的。出院时,心肺疾病患者比神经疾病患者更有能力进行测试。除第1秒用力呼气容积百分比和用力肺活量百分比外,所有结局指标均与残疾评分显著相关。外周肌肉锻炼的可行性最高,肺活量测定和腿部耐力最低。运动残疾主要由外周肌肉力量解释。应在这一特定人群中进行与方案驱动干预相关的非自主结局指标和测试的研究。

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