Korneva V A, Kuznetsova T Yu
Petrozavodsk State University, Petrozavodsk, Russia.
Ter Arkh. 2016;88(9):119-124. doi: 10.17116/terarkh2016889119-124.
Arterial wall stiffness is an early marker of cardiovascular diseases. The gold standard for assessment of the stiffness of large vessels is presently pulse wave velocity (PWV). Work is in progress on the study of the reference values of PWV in people of different genders and ages. 24-hour blood pressure (BP) monitoring is not only a procedure that can estimate diurnal BP variability, but also monitor the indicators of vascular wall stiffness in a number of cases over a 24-hour period. The given review highlights the pathophysiology of arterial stiffness, methods for its assessment, and the aspects of use in therapeutic practice.
动脉壁僵硬度是心血管疾病的早期标志物。目前,评估大血管僵硬度的金标准是脉搏波速度(PWV)。针对不同性别和年龄人群的PWV参考值的研究正在进行中。24小时血压(BP)监测不仅是一种可以评估血压昼夜变异性的方法,而且在许多情况下还能在24小时内监测血管壁僵硬度指标。本综述重点介绍了动脉僵硬度的病理生理学、评估方法以及在治疗实践中的应用方面。