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[健康与疾病中的脂联素]

[Adiponectin in health and disease].

作者信息

Tereshchenko I V, Kamenskikh Ya A, Suslina A A

机构信息

Acad. E.A. Vagner Perm State Medical University, Ministry of Health of Russia, Perm, Russia.

出版信息

Ter Arkh. 2016;88(12):126-132. doi: 10.17116/terarkh20168812126-132.

Abstract

Over the past 20 years after the discovery of adiponectin, much knowledge about its effect in health and disease has been gained. Adiponectin has antidiabetic, antiatherogenic, anti-inflammatory, immunomodulatory, metabolic, vasoprotective, and antiapoptotic properties. However, an understanding stems from the given literature review that much remains to be explored. Adiponectin has not yet commonly used in clinical practice, but cardiologists, endocrinologists, pediatricians, oncologists, and physicians of many specialties are interested in its preventive and therapeutic applications.

摘要

在脂联素被发现后的过去20年里,人们对其在健康和疾病中的作用有了很多了解。脂联素有抗糖尿病、抗动脉粥样硬化、抗炎、免疫调节、代谢、血管保护和抗凋亡特性。然而,从给定的文献综述中可以看出,仍有许多有待探索之处。脂联素尚未在临床实践中普遍使用,但心脏病学家、内分泌学家、儿科医生、肿瘤学家和许多专科的医生都对其预防和治疗应用感兴趣。

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