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腮腺良性肿瘤:339例患者的回顾性研究

Benign tumors of the parotid gland: a retrospective study of 339 patients.

作者信息

Quiriny Marie, Dekeyser Cécile, Moreau Michel, Digonnet Antoine, Willemse Esther, Vanbel Laurent, Andry Guy

机构信息

a Department of Surgery, Jules Bordet Institute , Université Libre de Bruxelles, Rue Héger-Bordet , Brussels , Belgium.

b Biostatistics Center, Jules Bordet Institute , Université Libre de Bruxelles, Rue Héger-Bordet , Brussels , Belgium.

出版信息

Acta Chir Belg. 2017 Aug;117(4):227-231. doi: 10.1080/00015458.2017.1287394. Epub 2017 Feb 10.

Abstract

AIM

Among 339 patients operated for benign tumor of the parotid gland: the recurrences and the postoperative complications rates were compared WITH those published in literature.

MATERIALS AND METHODS

About 339 patients operated: 274 primarily and 65 for recurrence or residual tumor.

VARIABLES

sex, age, surgical techniques, pre- or postoperative radiotherapy, histology, size and localization of the tumors, disease free intervals, recurrences and postoperative complications.

RESULTS

177 men and 162 women. Median age: 55 years and mean follow-up: 10.4 years. About 39 patients had adjuvant radiotherapy (11.5%). After primary surgery, four patients experienced recurrences (1.5%). After salvage surgery, eight patients recurred (12.3%). The recurrence rate was the highest among pleomorphic adenomas. Facial paralysis was more frequent after salvage surgery.

DISCUSSION

Recurrence rate 10 years later was lower after primary than after salvage surgery (p = 0.01). There was no relation between adjuvant radiotherapy and recurrence rate probably because the low rate of recurrences.

CONCLUSION

Recurrence rate after primary surgery is lower after superficial or total parotidectomy than after other surgical techniques. Pleomorphic adenomas have the highest rate of recurrences. Age and sex have no significant influence over the rate of recurrences. The most frequent postoperative complications are facial paralysis and Frey's syndrome.

摘要

目的

在339例接受腮腺良性肿瘤手术的患者中,比较复发率和术后并发症发生率与文献报道的情况。

材料与方法

约339例患者接受手术,其中274例为初次手术,65例为复发或残留肿瘤手术。

变量

性别、年龄、手术技术、术前或术后放疗、组织学、肿瘤大小和位置、无病间期、复发情况和术后并发症。

结果

男性177例,女性162例。中位年龄55岁,平均随访10.4年。约39例患者接受了辅助放疗(11.5%)。初次手术后,4例患者复发(1.5%)。挽救性手术后,8例患者复发(12.3%)。多形性腺瘤的复发率最高。挽救性手术后面神经麻痹更为常见。

讨论

初次手术后10年的复发率低于挽救性手术后(p = 0.01)。辅助放疗与复发率之间无相关性,可能是因为复发率较低。

结论

浅叶或全腮腺切除术后初次手术的复发率低于其他手术技术。多形性腺瘤的复发率最高。年龄和性别对复发率无显著影响。最常见的术后并发症是面神经麻痹和味觉出汗综合征。

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