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偶然发现的腮腺病变的临床病理特征。

Clinicopathological features of incidental parotid lesions.

机构信息

Michael E. DeBakey VA Medical Center, 2002 Holcombe Blvd, 77030, Houston, Texas, USA.

Jordan University of Science and Technology, Irbid, Jordan.

出版信息

Head Face Med. 2021 Mar 23;17(1):10. doi: 10.1186/s13005-021-00262-6.

Abstract

BACKGROUND

The purpose of this study is to determine the histopathological spectrum and risk of primary malignancy of asymptomatic parotid lesions incidentally discovered on cross-sectional imaging.

METHODS

Over a 10-year period, 154 patients underwent 163 ultrasound-guided parotid lesion biopsies at our institution. This retrospective chart review included 89 lesions in 87 patients with asymptomatic parotid lesions discovered on cross-sectional imaging studies performed for unrelated clinical indications. The histopathologic findings of all sampled lesions were reviewed. We evaluated the patient demographics and pathological diagnoses of sampled parotid lesions to determine the histopathological spectrum and risk of malignancy.

RESULTS

The average age was 67.5 years and 92 % were males. 25 % of patients had bilateral lesions. The average size of the parotid lesions was 1.5 cm and 91 % were located in the superficial lobe. 92.1 % of lesions were benign with Warthin tumor being the most common diagnosis followed by pleomorphic adenoma. 2.3 % of lesions were primary parotid malignant neoplasms, while 5.6 % were metastatic lesions in patients with known malignancy.

CONCLUSIONS

The incidence of primary parotid malignant neoplasm in asymptomatic incidentally discovered parotid lesions is low. Imaging or clinical follow-up may be considered in patients with incidental parotid lesions who prefer to avoid biopsy.

摘要

背景

本研究旨在确定偶然在影像学检查中发现的无症状腮腺病变的组织病理学谱和原发性恶性肿瘤的风险。

方法

在 10 年期间,我院对 154 名患者的 163 个超声引导下腮腺病变活检进行了研究。这项回顾性图表回顾研究包括 87 名无症状腮腺病变患者的 89 个病变,这些病变是在进行与临床无关的影像学检查时偶然发现的。对所有取样病变的组织病理学发现进行了回顾。我们评估了采样腮腺病变患者的人口统计学和病理诊断,以确定组织病理学谱和恶性肿瘤的风险。

结果

平均年龄为 67.5 岁,92%为男性。25%的患者有双侧病变。腮腺病变的平均大小为 1.5cm,91%位于浅叶。92.1%的病变为良性,其中最常见的诊断为沃辛肿瘤,其次是多形性腺瘤。2.3%的病变为原发性腮腺恶性肿瘤,而 5.6%为有已知恶性肿瘤的患者的转移性病变。

结论

在偶然发现的无症状腮腺病变中,原发性腮腺恶性肿瘤的发生率较低。对于偶然发现的腮腺病变患者,如果他们愿意避免活检,可以考虑影像学或临床随访。

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本文引用的文献

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Parotid Gland Tumors: 2-Year Prospective Clinicopathological Study.腮腺肿瘤:2年前瞻性临床病理研究
Ann Maxillofac Surg. 2019 Jan-Jun;9(1):103-109. doi: 10.4103/ams.ams_179_18.
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Benign tumors of the parotid gland: a retrospective study of 339 patients.腮腺良性肿瘤:339例患者的回顾性研究
Acta Chir Belg. 2017 Aug;117(4):227-231. doi: 10.1080/00015458.2017.1287394. Epub 2017 Feb 10.
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Clinical significance of parotid gland incidentalomas on (18)F-FDG PET/CT.腮腺偶发瘤在(18)F-FDG PET/CT上的临床意义
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