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巴贝斯虫病:肾移植术后脓毒症的一种罕见病因及文献综述

Babesiosis: An unusual cause of sepsis after kidney transplantation and review of the literature.

作者信息

Ather Imtiaz, Pourafshar Negiin, Schain Denise, Gupte Asmita, Casey Michael J

机构信息

Division of Nephrology, Hypertension, and Renal Transplantation, Department of Medicine, University of Florida, Gainesville, FL, USA.

Division of Nephrology, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

出版信息

Transpl Infect Dis. 2017 Oct;19(5). doi: 10.1111/tid.12740. Epub 2017 Jul 28.

Abstract

We report a unique case of babesiosis presenting as sepsis after kidney transplantation. A 70-year-old female kidney transplant recipient presented with fever, hemolytic anemia, and acute kidney injury, and met three of four systemic inflammatory response syndrome criteria. Serology was positive for Babesia microti, confirmed by polymerase chain reaction. The patient was treated with atovaquone and azithromycin and made a full recovery. Reports of babesiosis after solid organ transplantation are rare, with only four prior cases reported in the literature. We report the first case of babesiosis, to our knowledge, presenting as sepsis that was successfully treated after solid organ transplantation.

摘要

我们报告了一例肾移植后表现为脓毒症的巴贝斯虫病罕见病例。一名70岁女性肾移植受者出现发热、溶血性贫血和急性肾损伤,符合四项全身炎症反应综合征标准中的三项。血清学检测微小巴贝斯虫呈阳性,经聚合酶链反应确认。患者接受了阿托伐醌和阿奇霉素治疗并完全康复。实体器官移植后巴贝斯虫病的报告很少,文献中仅报道过4例先前病例。据我们所知,我们报告了首例实体器官移植后表现为脓毒症且成功治愈的巴贝斯虫病病例。

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