Segal Jonathan, Lagundoye Ayodele, Carter Martyn
St Mark's Hospital, Harrow, UK.
Gastroenterology, Lister Hospital, Stevenage, UK.
BMJ Case Rep. 2017 Jun 20;2017:bcr-2017-219386. doi: 10.1136/bcr-2017-219386.
A 50-year-old male with a 7 month history of progressive dysphagia to solids then subsequently to liquids. He underwent a diagnostic gastroscopy which was normal. A further barium swallow suggested achalasia. He was referred to a tertiary centre, where he underwent pH and manometry studies which confirmed a diagnosis of achalasia. He was referred for a laparoscopic cardiomyotomy, and at surgery there was a suspected tumour at the gastro-oesophageal junction. A follow-up endoscopy with biopsies was normal. Following this, a positron emission tomography scan showed T3 distal oesophageal cancer with no nodal involvement or distal metastasis. An attempt at oesophagectomy was performed, but at operation there was locally advanced carcinoma infiltrating the coeliac axis. He is currently undergoing palliative chemotherapy.
一名50岁男性,有7个月进行性吞咽固体食物困难病史,随后发展为吞咽液体食物困难。他接受了诊断性胃镜检查,结果正常。进一步的钡餐造影提示贲门失弛缓症。他被转诊至三级中心,在那里进行了pH值和测压研究,确诊为贲门失弛缓症。他被转诊接受腹腔镜贲门肌切开术,手术时在胃食管交界处怀疑有肿瘤。后续的内镜活检结果正常。在此之后,正电子发射断层扫描显示为T3期食管远端癌,无淋巴结受累或远处转移。尝试进行了食管切除术,但手术时发现局部晚期癌已浸润腹腔干。他目前正在接受姑息化疗。