Prishchepa A V, Danilov A B
Sechenov First Moscow State Medical University, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117(5):94-102. doi: 10.17116/jnevro20171175194-102.
The overview is dedicated to the neuroimmunological mechanisms of headache development and chronification. Based on the analyzed data, the authors determined the relationship between immunological parameters and duration, intensity and other characteristics of this disease. These findings confirm that immunocompetent cells can be used as headache biomarkers and predictors of treatment efficacy. Questions about the role of separate parts of the immune system in the development and maintenance of a headache require further research. Studies of humoral immunity appeared to be very promising.
本综述致力于探讨头痛发生及慢性化的神经免疫机制。基于分析数据，作者确定了免疫参数与该疾病的持续时间、强度及其他特征之间的关系。这些发现证实免疫活性细胞可作为头痛的生物标志物及治疗效果的预测指标。关于免疫系统各部分在头痛发生及维持中的作用问题，仍需进一步研究。体液免疫的研究似乎非常有前景。
