Oelssner W, Peinhardt G, Büge A
Pharmazie. 1985 May;40(5):341-2.
By introduction of fluorine into the position 7 of butaperazine, chlorpromazine, methoxypromazine, perphenazine, prochlorperazine or into the position 3 of promazine derivatives are obtained with higher affinities for the 3H-spiroperidol binding site of the dopamine receptor compared with the corresponding substances free of fluorine.
通过将氟引入丁酰拉嗪、氯丙嗪、甲氧丙嗪、奋乃静、丙氯拉嗪的7位,或引入丙嗪衍生物的3位,可得到与相应的无氟物质相比,对多巴胺受体的3H-螺哌啶醇结合位点具有更高亲和力的物质。