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[鼠疫耶尔森菌中的黏附菌毛]

[Adhesion pili in Yersinia pestis].

作者信息

Vodop'ianov S O, Mishan'kin B N

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1985 Jun(6):13-7.

PMID:2863905
Abstract

Y. pestis cells cultivated at 37 degrees C are capable of agglutinating red blood cells of some animals, which is due to the appearance of pili. The adhesion pili consist of protein subunits with a molecular weight of the order of 12000 daltons, their isoionic point being at pH 4.7. The reaction of hemagglutination was inhibited by the mixture of ganglyosides, while the preliminary treatment of red blood cells with neuraminidases increased its effectiveness. The pili are supposed to take part in the expression of virulence.

摘要

在37摄氏度培养的鼠疫耶尔森氏菌细胞能够凝集某些动物的红细胞,这是由于菌毛的出现。粘附菌毛由分子量约为12000道尔顿的蛋白质亚基组成,其等离子点为pH 4.7。神经节苷脂混合物可抑制血凝反应,而用神经氨酸酶对红细胞进行预处理可提高其有效性。推测菌毛参与了毒力的表达。

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