用于X连锁凋亡抑制蛋白缺陷型噬血细胞性淋巴组织细胞增生症的干扰素γ阻断、苏消安预处理及αβ T细胞去除的外周血干细胞移植 - Suppr

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超能文献

IFNɣ Block, Treosulfan Conditioning and αβ T Cell Deplete PBSCT for XIAP-Deficient HLH.

作者信息

O'Rafferty Ciara, Velangi Mark, Lawson Sarah, Hiwarkar Prashant, Motwani Jayashree

机构信息

Department of Haematology, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK.

出版信息

J Clin Immunol. 2017 Aug;37(6):511-513. doi: 10.1007/s10875-017-0413-7. Epub 2017 Jun 21.

DOI:10.1007/s10875-017-0413-7

PMID:28639166

Abstract

摘要

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本文引用的文献

Treosulfan-based conditioning regimen for children and adolescents with hemophagocytic lymphohistiocytosis.以三氟胸苷为基础的儿童和青少年噬血细胞性淋巴组织细胞增生症的预处理方案。

Haematologica. 2014 Jan;99(1):180-4. doi: 10.3324/haematol.2013.094730. Epub 2013 Oct 25.

Allogeneic hematopoietic cell transplantation for XIAP deficiency: an international survey reveals poor outcomes.XIAP 缺陷的异基因造血细胞移植：国际调查显示预后不良。

Blood. 2013 Feb 7;121(6):877-83. doi: 10.1182/blood-2012-06-432500. Epub 2012 Nov 6.

Reduced-intensity conditioning significantly improves survival of patients with hemophagocytic lymphohistiocytosis undergoing allogeneic hematopoietic cell transplantation.降低强度的预处理方案可显著改善噬血细胞性淋巴组织细胞增生症患者接受异基因造血细胞移植后的生存情况。

Blood. 2010 Dec 23;116(26):5824-31. doi: 10.1182/blood-2010-04-282392. Epub 2010 Sep 20.

Neutralization of IFNgamma defeats haemophagocytosis in LCMV-infected perforin- and Rab27a-deficient mice.中和 IFNγ 可阻止 LCMV 感染的穿孔素和 Rab27a 缺陷型小鼠的噬血细胞现象。

EMBO Mol Med. 2009 May;1(2):112-24. doi: 10.1002/emmm.200900009.

A large-scale method for the selective depletion of alphabeta T lymphocytes from PBSC for allogeneic transplantation.一种从外周血干细胞中选择性清除αβ T淋巴细胞用于异基因移植的大规模方法。

Cytotherapy. 2007;9(8):746-54. doi: 10.1080/14653240701644000. Epub 2007 Oct 4.

An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder.噬血细胞性淋巴组织细胞增生症（HLH）的动物模型：CD8 + T细胞和干扰素γ对该病症至关重要。

Blood. 2004 Aug 1;104(3):735-43. doi: 10.1182/blood-2003-10-3413. Epub 2004 Apr 6.

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