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《化脓性汗腺炎患者管理指南:共识文件》。

Approach to the Management of Patients With Hidradenitis Suppurativa: A Consensus Document.

机构信息

1 Department of Medicine (Dermatology), University of Toronto, Toronto, ON, Canada.

2 Sherbrooke University, Sherbrooke, QC, Canada.

出版信息

J Cutan Med Surg. 2017 Nov/Dec;21(6):513-524. doi: 10.1177/1203475417716117. Epub 2017 Jun 22.

Abstract

BACKGROUND

Hidradenitis suppurativa (HS) is a painful, debilitating, and poorly understood condition, which is suboptimally diagnosed, managed, and treated. Evidence supporting various treatment modalities is sparse.

OBJECTIVES

To incorporate scientific evidence and expert opinions to develop useful guidance for the evaluation and management of patients with HS.

METHODS

An expert panel of Canadian dermatologists and surgeons developed statements and recommendations based on available evidence and clinical experience. The statements and recommendations were subjected to analysis and refinement by the panel, and voting was conducted using a modified Delphi technique with a prespecified cutoff agreement of 75%.

RESULTS

Ten specific statements and recommendations were accepted by the expert panel. These were grouped into 4 domains: diagnosis and assessment, treatment and management, comorbidities and a multidisciplinary approach, and education.

CONCLUSIONS

These statements and recommendations will serve to increase awareness of HS and provide a framework for decisions involving diagnosis and management. Evidence suggests that antibacterial and anti-tumour necrosis factor therapies are effective in the treatment of HS. This is supported by the clinical experience of the authors. Further clinical research and the establishment of multidisciplinary management teams will continue to advance management of HS in Canada.

摘要

背景

化脓性汗腺炎(HS)是一种痛苦、使人虚弱且了解甚少的疾病,其诊断、管理和治疗效果均不佳。支持各种治疗方法的证据很少。

目的

结合科学证据和专家意见,为 HS 患者的评估和管理制定有用的指导。

方法

加拿大皮肤科医生和外科医生的专家小组根据现有证据和临床经验制定了陈述和建议。该小组对陈述和建议进行了分析和改进,并使用修改后的 Delphi 技术进行投票,预设的共识表决率为 75%。

结果

专家小组接受了 10 项具体的陈述和建议。这些陈述和建议分为 4 个领域:诊断和评估、治疗和管理、合并症和多学科方法以及教育。

结论

这些陈述和建议将有助于提高对 HS 的认识,并为诊断和管理相关决策提供框架。有证据表明,抗菌和抗肿瘤坏死因子治疗对 HS 的治疗有效。这得到了作者临床经验的支持。进一步的临床研究和建立多学科管理团队将继续推进加拿大 HS 的管理。

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