Sano Informed Prescribing, Sano Laboratories , Franklin, Tennessee 37067, United States.
ACS Chem Neurosci. 2017 Aug 16;8(8):1641-1644. doi: 10.1021/acschemneuro.7b00209. Epub 2017 Jun 22.
There are multiple treatment options for depression, anxiety, psychosis, and other psychiatric disorders, and psychiatry patients are often comorbid with complex, polypharmacy treatment regimens. Unlike cardiovascular disease and diabetes, there are no readily available biomarkers to gauge treatment success with psychotropic medications, often resulting in subjective determination of medication therapy effectiveness. The physiochemical properties of psychiatric medications in general lend themselves to quantitative measurement in blood, offering an avenue to optimize treatment for each patient. Herein, we describe a novel application that employs comprehensive therapeutic drug monitoring of both psychiatric and nonpsychiatric medications to holistically personalize therapy for complex psychiatry patients.
有多种治疗抑郁症、焦虑症、精神病和其他精神疾病的选择，精神科患者经常同时患有复杂的、多药物治疗方案。与心血管疾病和糖尿病不同，没有现成的生物标志物来衡量精神药物治疗的成功，这通常导致药物治疗效果的主观判断。一般来说，精神药物的理化性质使其能够在血液中进行定量测量，为优化每位患者的治疗提供了途径。在此，我们描述了一种新的应用，它采用精神科和非精神科药物的综合治疗药物监测，全面实现复杂精神科患者的个体化治疗。
