Campos Dulcinea Maria Barbosa, Barbosa Alverne Passos, Oliveira Jayrson Araújo de, Tavares Giovana Galvão, Cravo Pedro Vitor Lemos, Ostermayer Alejandro Luquetti
Programa de Pós-Graduação em Sociedade Tecnologia e Meio Ambiente e Curso de Farmácia, Centro Universitário de Anápolis-UniEVANGÉLICA, Anápolis, Goiás, Brazil.
Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Goiás, Brazil.
PLoS Negl Trop Dis. 2017 Jun 22;11(6):e0005510. doi: 10.1371/journal.pntd.0005510. eCollection 2017 Jun.
Lagochilascariasis is a parasitic disease caused by a helminth of the order Ascaroidea, genus Lagochilascaris that comprises 6 species, among which only Lagochilascaris minor Leiper, 1909, is implicated in the human form of the disease. It is remarkable that the majority of cases of human lagochilascariasis in the Americas have been reported in Brazil. The natural definitive hosts of this parasite seem to be wild felines and canines. Lagochilascariasis is mostly a chronic human disease that can persist for several years, in which the parasite burrows into the subcutaneous tissues of the neck, paranasal sinuses, and mastoid. L. minor exhibits remarkable ability to migrate through the tissues of its hosts, destroying even bone tissue. Fatal cases have been described in which the parasite was found in the lungs or central nervous system. Treatment is often palliative, with recurrence of lesions. This paper summarizes the main features of the disease and its etiologic agent, including prevalence, life cycle, clinical course, and treatment.
唇颚蛔蚴病是一种由蛔目、唇颚蛔属的蠕虫引起的寄生虫病，该属包含6个物种，其中只有1909年利珀发现的小型唇颚蛔与人类形式的疾病有关。值得注意的是，美洲大多数人类唇颚蛔蚴病病例都在巴西被报道。这种寄生虫的天然终宿主似乎是野生猫科动物和犬科动物。唇颚蛔蚴病大多是一种慢性人类疾病，可持续数年，寄生虫会钻入颈部、鼻窦和乳突的皮下组织。小型唇颚蛔在其宿主组织中具有显著的迁移能力，甚至能破坏骨组织。已有致命病例的描述，其中在肺部或中枢神经系统发现了寄生虫。治疗通常是姑息性的，病变会复发。本文总结了该疾病及其病原体的主要特征，包括患病率、生命周期、临床病程和治疗方法。
