Medina Rebeca P, de Moura Vagner M, da Silva Cleuza C, de Oliveira Cecília M A, Kato Lucilia, Pomini Armando M, de Carvalho João E, Ruiz Ana Lúcia T G, Bersani-Amado Ciomar A, Santin Silvana M O
a Departamento de Química , Universidade Estadual de Maringá , Maringá , Paraná , Brazil.
b Instituto de Química, Universidade Federal de Goiás , Goiânia , Brazil.
Nat Prod Res. 2018 Jun;32(11):1357-1360. doi: 10.1080/14786419.2017.1344654. Epub 2017 Jun 23.
The crude extract and fractions from the branches of Ixora brevifolia, a tree found in the Brazilian Cerrado, were tested for anti-inflammatory and in vitro antiproliferative effects. The crude extract and n-hexane fraction exhibited significant inhibition of ear oedema in mice, while n-hexane-precipitated and chloroform fractions strongly inhibited the myeloperoxidase activity in ear tissue. The n-hexane and n-hexane-precipitated fractions showed strong growth inhibition for glioma cell line and the hydromethanolic fraction inhibited the growth of leukaemia cell line.
对在巴西塞拉多发现的一种树木——短叶龙船花枝条的粗提物和馏分进行了抗炎和体外抗增殖作用测试。粗提物和正己烷馏分对小鼠耳部水肿表现出显著抑制作用，而正己烷沉淀馏分和氯仿馏分强烈抑制耳部组织中的髓过氧化物酶活性。正己烷和正己烷沉淀馏分对胶质瘤细胞系表现出强烈的生长抑制作用，而水甲醇馏分抑制白血病细胞系的生长。
