Brockman R P, Laarveld B
Comp Biochem Physiol A Comp Physiol. 1985;81(2):255-7. doi: 10.1016/0300-9629(85)90131-8.
The net productions of acetate and beta-hydroxybutyrate by the liver and portal-drained viscera were determined before and during insulin plus glucose infusions. Glucose was infused at rates to maintain euglycemia. During insulin infusion the net hepatic productions of beta-hydroxybutyrate and acetate were reduced to a greater extent than could be accounted for by a reduction in provision of free fatty acids to the liver. It is concluded that insulin has a direct anti-ketogenic effect on the ovine liver.
在输注胰岛素加葡萄糖之前及期间，测定了肝脏和门静脉引流脏器中乙酸盐和β-羟基丁酸盐的净生成量。以维持血糖正常的速率输注葡萄糖。在输注胰岛素期间，肝脏中β-羟基丁酸盐和乙酸盐的净生成量降低的程度，比因向肝脏提供的游离脂肪酸减少所能解释的程度更大。得出的结论是，胰岛素对绵羊肝脏具有直接的抗生酮作用。
