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一例“迟发性”术后甲状旁腺功能减退症病例。

A Case of "Late" Postsurgical Hypoparathyroidism.

作者信息

Simões Cesar Augusto, Costa M K, Comerlato L B, Ogusco A A, Araújo Filho V, Dedivitis R A, Cernea C R

机构信息

Department of Head and Neck Surgery, University of Santo Amaro School of Medicine, São Paulo, SP, Brazil.

University of Santo Amaro School of Medicine, São Paulo, SP, Brazil.

出版信息

Case Rep Endocrinol. 2017;2017:3962951. doi: 10.1155/2017/3962951. Epub 2017 May 31.

DOI:10.1155/2017/3962951
PMID:28642829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5469994/
Abstract

INTRODUCTION

Postsurgical hypoparathyroidism normally occurs a short time after thyroid surgery in form of two clinical syndromes of different etiology and prognosis. The first is transitory and might spontaneously recover within a few weeks or months. The second is permanent and needs a definitive treatment. Only few cases of hypoparathyroidism clinically evident after many years from surgery have been reported.

CASE REPORT

A case of hypoparathyroidism clinically evident only three and a half years after surgery is reported. Our findings and review of a few cases reported by medical literature suggest the existence of a third form of postsurgical hypoparathyroidism, characterized by a late beginning.

摘要

引言

术后甲状旁腺功能减退通常在甲状腺手术后短时间内出现,表现为两种病因和预后不同的临床综合征。第一种是暂时性的,可能在几周或几个月内自发恢复。第二种是永久性的,需要确定性治疗。仅有少数几例在手术后多年临床才出现明显甲状旁腺功能减退的病例被报道。

病例报告

本文报告了一例术后三年半才出现明显临床症状的甲状旁腺功能减退病例。我们的研究结果以及对医学文献中报道的少数病例的回顾表明,存在第三种术后甲状旁腺功能减退形式,其特点是发病较晚。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f3/5469994/2c6f9e2f7ddf/CRIE2017-3962951.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f3/5469994/2c6f9e2f7ddf/CRIE2017-3962951.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f3/5469994/2c6f9e2f7ddf/CRIE2017-3962951.001.jpg

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本文引用的文献

1
Does preoperative 25-hydroxyvitamin D status significantly affect the calcium kinetics after total thyroidectomy?术前 25-羟维生素 D 状态是否显著影响全甲状腺切除术后的钙动力学?
World J Surg. 2013 Jul;37(7):1592-8. doi: 10.1007/s00268-013-2015-8.
2
Hypocalcemia and hypoparathyroidism after total thyroidectomy: a clinical biological study and surgical considerations.全甲状腺切除术后的低钙血症和甲状旁腺功能减退:一项临床生物学研究及手术考量
Int J Surg Investig. 2000;2(2):99-105.
3
Does it exist also a "late" post-surgical hypoparathyroidism?是否也存在“迟发性”术后甲状旁腺功能减退症?
Riv Eur Sci Med Farmacol. 1994 Sep-Dec;16(5-6):99-101.