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Serum neuroleptic levels and extrapyramidal side effects in patients treated with amoxapine.

作者信息

Gaffney G R, Tune L E

出版信息

J Clin Psychiatry. 1985 Oct;46(10):428-9.

PMID:2864332
Abstract

Serum neuroleptic levels were measured by radioreceptor assay in patients treated with the antidepressant amoxapine. When compared to standard neuroleptics, amoxapine produced relatively weak neuroleptic activity. Amoxapine dose correlated significantly with serum neuroleptic level. Three of eight patients developed significant extrapyramidal side effects. Neither dose of amoxapine nor neuroleptic level correlated with the presence or severity of EPS.

摘要

相似文献

1
Serum neuroleptic levels and extrapyramidal side effects in patients treated with amoxapine.
J Clin Psychiatry. 1985 Oct;46(10):428-9.
2
Amoxapine and neuroleptic side effects: a case report.阿莫沙平与抗精神病药物副作用:一例报告
Am J Psychiatry. 1983 Sep;140(9):1233-5. doi: 10.1176/ajp.140.9.1233.
3
[Amoxapine. An antidepressant responsible for extrapyramidal side effects?].[阿莫沙平。一种导致锥体外系副作用的抗抑郁药?]
Therapie. 1985 May-Jun;40(3):187-90.
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Double-blind comparison of amoxapine and imipramine in the treatment of depressed patients.阿莫沙平与丙咪嗪治疗抑郁症患者的双盲对照研究。
J Clin Psychiatry. 1984 Feb;45(2):54-56, 57-9.
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Amoxapine-induced seizures: case reports.阿莫沙平诱发癫痫发作:病例报告。
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Amoxapine and extrapyramidal symptoms.阿莫沙平与锥体外系症状。
J Clin Psychiatry. 1984 Sep;45(9):407.
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Amoxapine-induced extrapyramidal effects.阿莫沙平引起的锥体外系反应。
Psychosomatics. 1986 Jun;27(6):464, 468. doi: 10.1016/S0033-3182(86)72679-0.
8
Amoxapine: neuroleptic as well as antidepressant?阿莫沙平:既是抗精神病药又是抗抑郁药?
Am J Psychiatry. 1982 Sep;139(9):1165-7. doi: 10.1176/ajp.139.9.1165.
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J Clin Psychopharmacol. 2007 Dec;27(6):575-81. doi: 10.1097/jcp.0b013e31815a4424.
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A case of akinesia induced by amoxapine.
Am J Psychiatry. 1984 Feb;141(2):283-4. doi: 10.1176/ajp.141.2.283.

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Antipsychotics in older patients. A safety perspective.老年患者使用抗精神病药物:安全性视角
Drugs Aging. 1995 Apr;6(4):312-23. doi: 10.2165/00002512-199506040-00006.
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Antidepressants. A comparative review of the clinical pharmacology and therapeutic use of the 'newer' versus the 'older' drugs.抗抑郁药。“新型”与“传统”药物临床药理学与治疗用途的比较综述。
Drugs. 1989 May;37(5):713-38. doi: 10.2165/00003495-198937050-00006.