Baggerman C, Pathmamanoharan C, Spies F, Joosten J G, Junginger H E
J Pharm Pharmacol. 1985 Aug;37(8):521-7. doi: 10.1111/j.2042-7158.1985.tb03059.x.
Endotoxins of Escherichia coli, Salmonella abortus equi and Serratia marcescens were examined using freeze-etch electronmicroscopy and light scattering techniques, with emphasis on their aggregation state. These endotoxins show distinct features of particle size and mass and they may be affected by the presence or absence of Ca2+ ions. No important differences were observed in the particle characteristics of the respective endotoxins in various infusion fluids.
使用冷冻蚀刻电子显微镜和光散射技术对大肠杆菌、马流产沙门氏菌和粘质沙雷氏菌的内毒素进行了检查，重点是它们的聚集状态。这些内毒素显示出颗粒大小和质量的明显特征，并且它们可能受Ca2+离子存在与否的影响。在各种输液中，未观察到各内毒素的颗粒特征有重要差异。
