Kim Dong-Eun, Park Ji-Yun, Ha Hyeonuk, Yoon Geum-Jin, Cho Bang-Hoon, Lee Seung-Han
*Department of Neurology, Chonnam National University Medical School, Gwangju †Department of Neurology, Ulsan University Hospital, Ulsan, Korea.
Neurologist. 2017 Jul;22(4):138-140. doi: 10.1097/NRL.0000000000000127.
Cluster headache (CH) is characterized by attacks of severe periorbital pain associated with autonomic symptoms. As with other forms of primary headache, structural lesions should be excluded, particularly if the headache presents with an atypical pattern.
We report a 41-year-old woman who had no previous history of primary headache and showed a poor response to medication for CH. The patient was finally diagnosed as secondary headache with CH feature due to focal myelitis at the cervical level of the spinal cord. A strong positive Enzyme-linked Immunosorbent Assay test for Toxocara canis antibodies helped us to make a diagnosis of cervical Toxocara myelitis. After starting treatment with intravenous methylprednisolone and albendazole, her headache gradually improved with abortive and preventive treatment for CH.
We suggest that neuroimaging of the upper cervical cord as well as the brain is important when CH is showing an atypical clinical course. Cervical Toxocara myelitis might be a possible cause of secondary headache with CH feature.
丛集性头痛(CH)的特征是发作性严重眶周疼痛并伴有自主神经症状。与其他形式的原发性头痛一样,应排除结构性病变,尤其是当头痛表现为非典型模式时。
我们报告一名41岁女性,既往无原发性头痛病史,对CH药物治疗反应不佳。该患者最终被诊断为继发于脊髓颈段局灶性脊髓炎的具有CH特征的继发性头痛。犬弓首线虫抗体酶联免疫吸附试验强阳性有助于我们诊断颈段犬弓首线虫脊髓炎。在开始静脉注射甲泼尼龙和阿苯达唑治疗后,她的头痛在采用CH的发作期和预防性治疗后逐渐改善。
我们建议,当CH呈现非典型临床病程时,对上颈段脊髓以及脑部进行神经影像学检查很重要。颈段犬弓首线虫脊髓炎可能是具有CH特征的继发性头痛的一个可能原因。