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与犬弓首蛔虫感染相关的嗜酸性粒细胞增多性脑脊膜炎和脊髓炎。

Eosinophilic pleocytosis and myelitis related to Toxocara canis infection.

作者信息

Goffette S, Jeanjean A P, Duprez T P, Bigaignon G, Sindic C J

机构信息

Service de Neurologie, Cliniques Universitaires Saint-Luc, 1200 Brussels, Belgium.

出版信息

Eur J Neurol. 2000 Nov;7(6):703-6. doi: 10.1046/j.1468-1331.2000.00123.x.

Abstract

Toxocara canis causes the visceral larva migrans syndrome in which central nervous involvement is rare. We report the case of a 40-year-old woman presenting with a subacute weakness of the right leg and dysaesthesiae in the right Th8-Th10 dermatomas. Spinal magnetic resonance imaging examination showed abnormal hyperintensity within the spinal cord. Cerebrospinal fluid analysis revealed eosinophilic pleocytosis. Antibody titres to Toxocara canis were higher in the cerebrospinal fluid than in the serum. Treatment using mebendazole led to a complete clinical recovery, normalization of cerebrospinal fluid parameters and improvement in spinal magnetic resonance imaging abnormalities.

摘要

犬弓首蛔虫可引起内脏幼虫移行症综合征,其中中枢神经系统受累较为罕见。我们报告了一例40岁女性病例,该患者表现为右腿亚急性无力以及胸8至胸10右侧皮节感觉异常。脊髓磁共振成像检查显示脊髓内有异常高信号。脑脊液分析显示嗜酸性粒细胞增多。脑脊液中犬弓首蛔虫抗体滴度高于血清。使用甲苯咪唑治疗后临床完全康复,脑脊液参数恢复正常,脊髓磁共振成像异常也有所改善。

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