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肾肿瘤的当代治疗:北欧国家的问卷调查(NORENCA-I研究)

Contemporary treatment of renal tumors: a questionnaire survey in the Nordic countries (the NORENCA-I study).

作者信息

Nisen Harry, Järvinen Petrus, Fovaeus Magnus, Guðmundsson Eirikur, Kromann-Andersen Bjarne, Ljungberg Börje, Lund Lars, Nilsen Frode, Sundqvist Pernilla, Beisland Christian

机构信息

a Department of Urology , Helsinki University Hospital , Helsinki , Finland.

b Department of Urology , Sahlgrenska University Hospital , Gothenburg , Sweden.

出版信息

Scand J Urol. 2017 Oct;51(5):360-366. doi: 10.1080/21681805.2017.1326524. Epub 2017 Jun 23.

DOI:10.1080/21681805.2017.1326524
PMID:28644697
Abstract

OBJECTIVE

The five Nordic countries comprise 25 million people, and have similar treatment traditions and healthcare systems. To take advantage of these similarities, a collaborative group (Nordic Renal Cancer Group, NORENCA) was founded in 2015.

MATERIALS AND METHODS

A questionnaire of 17 questions on renal tumor management and surgical education was designed and sent to 91 institutions performing renal tumor surgery in 2015. The response rate was 68% (62 hospitals), including 28 academic, 25 central and nine district hospitals. Hospital volume was defined as low (LVH: < 20 operations), intermediate (IVH: 20-49 operations), high (HVH: 50-99) and very high (VHVH: ≥ 100). Descriptive statistics were performed.

RESULTS

Fifteen centers were LVH, 16 IVH, 21 HVH and 10 VHVH. Of all 3828 kidney tumor treatments, 55% were radical nephrectomies (RNs), 37% partial nephrectomies (PNs) and 8% thermoablations. For RN and PN, the percentages of open, laparoscopic and robotic approaches were 47%, 40%, 13% and 47%, 20%, 33%, respectively. The mean complication rate (Clavien-Dindo 3-5) was 4.9%, and 30 day mortality (TDM) was 0.5%. The median length of hospital stay was 4 days. Training with a simulator, black box or animal laboratory was possible in 48%, 74% and 21% of institutions, respectively.

CONCLUSIONS

Despite some differences between countries, the data suggest an overall general common Nordic treatment attitude for renal tumors. Furthermore, the data demonstrate high adherence to international standards, with a high proportion of PN and acceptable rates for major complications and TDM.

摘要

目的

北欧五国共有2500万人口,且有着相似的治疗传统和医疗体系。为利用这些相似之处,一个协作组(北欧肾癌组,NORENCA)于2015年成立。

材料与方法

设计了一份包含17个关于肾肿瘤管理和外科教育问题的问卷,并于2015年发送给91家进行肾肿瘤手术的机构。回复率为68%(62家医院),包括28家学术医院、25家中部医院和9家地区医院。医院手术量被定义为低(LVH:<20例手术)、中(IVH:20 - 49例手术)、高(HVH:50 - 99例手术)和非常高(VHVH:≥100例手术)。进行了描述性统计。

结果

15个中心为LVH,16个为IVH,21个为HVH,10个为VHVH。在所有3828例肾肿瘤治疗中,55%为根治性肾切除术(RN),37%为部分肾切除术(PN),8%为热消融术。对于RN和PN,开放、腹腔镜和机器人手术方式的百分比分别为47%、40%、13%和47%、20%、33%。平均并发症发生率(Clavien - Dindo 3 - 5级)为4.9%,30天死亡率(TDM)为0.5%。住院时间中位数为4天。分别有48%、74%和21%的机构可以使用模拟器、黑箱或动物实验室进行培训。

结论

尽管各国之间存在一些差异,但数据表明北欧对肾肿瘤总体上有共同的治疗态度。此外,数据显示高度遵循国际标准,PN比例高,主要并发症和TDM发生率可接受。

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