• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

首次未经治疗的强直阵挛性发作后的预后。

Prognosis after a first untreated tonic-clonic seizure.

作者信息

Elwes R D, Chesterman P, Reynolds E H

出版信息

Lancet. 1985 Oct 5;2(8458):752-3. doi: 10.1016/s0140-6736(85)90631-2.

DOI:10.1016/s0140-6736(85)90631-2
PMID:2864487
Abstract

The prognosis for seizure recurrence was assessed in 133 patients who presented at a median of 1 day after a first-ever tonic-clonic seizure. The cumulative probability of recurrence was 20% by 1 month, 28% by 2 months, 32% by 3 months, 46% by 6 months, 62% by 1 year, and 71% by 3 and 4 years. After a first seizure epilepsy is likely to develop in the majority of patients.

摘要

对首次强直阵挛发作后中位时间1天就诊的133例患者进行了癫痫复发预后评估。复发的累积概率在1个月时为20%,2个月时为28%,3个月时为32%,6个月时为46%,1年时为62%,3年和4年时为71%。首次发作后,大多数患者可能会发展为癫痫。

相似文献

1
Prognosis after a first untreated tonic-clonic seizure.首次未经治疗的强直阵挛性发作后的预后。
Lancet. 1985 Oct 5;2(8458):752-3. doi: 10.1016/s0140-6736(85)90631-2.
2
Lamotrigine adjunctive therapy among children and adolescents with primary generalized tonic-clonic seizures.拉莫三嗪辅助治疗儿童和青少年原发性全面性强直阵挛发作。
Pediatrics. 2006 Aug;118(2):e371-8. doi: 10.1542/peds.2006-0148. Epub 2006 Jul 17.
3
Idiopathic generalised epilepsy of adult onset: clinical syndromes and genetics.成人起病的特发性全身性癫痫:临床综合征与遗传学
J Neurol Neurosurg Psychiatry. 2003 Feb;74(2):192-6. doi: 10.1136/jnnp.74.2.192.
4
Epileptology of the first tonic-clonic seizure in adults and prediction of seizure recurrence.成人首次强直-阵挛性发作的癫痫学及发作复发预测
Epileptic Disord. 2018 Dec 1;20(6):490-501. doi: 10.1684/epd.2018.1014.
5
Age-related "Sleep/nocturnal" tonic and tonic clonic seizure clusters are underdiagnosed in patients with Dravet Syndrome.在患有德拉韦特综合征的患者中,与年龄相关的“睡眠/夜间”强直和强直阵挛发作簇未得到充分诊断。
Epilepsy Behav. 2017 Sep;74:33-40. doi: 10.1016/j.yebeh.2017.05.037. Epub 2017 Jul 3.
6
Long-term seizure outcome after corpus callosotomy: a retrospective analysis of 95 patients.胼胝体切开术后的长期癫痫发作结果:95例患者的回顾性分析。
J Neurosurg. 2009 Feb;110(2):332-42. doi: 10.3171/2008.3.17570.
7
[Juvenile myoclonic epilepsy].
Rev Neurol (Paris). 1990;146(12):719-25.
8
Myoclonic astatic epilepsy: an age-dependent epileptic syndrome with favorable seizure outcome but variable cognitive evolution.肌阵挛失神癫痫:一种与年龄相关的癫痫综合征,发作结局良好,但认知演变存在差异。
Epilepsy Res. 2011 Nov;97(1-2):133-41. doi: 10.1016/j.eplepsyres.2011.07.021. Epub 2011 Aug 27.
9
Epilepsy with myoclonic absences: Electroclinical characteristics in a distinctive pediatric epilepsy phenotype.伴有肌阵挛失神发作的癫痫:一种独特的小儿癫痫表型的电临床特征
Epilepsy Behav. 2016 Nov;64(Pt A):242-247. doi: 10.1016/j.yebeh.2016.08.023. Epub 2016 Oct 19.
10
The treatable epilepsies. (First of Two Parts).可治疗的癫痫(两部分中的第一部分)
N Engl J Med. 1983 Jun 23;308(25):1508-14. doi: 10.1056/NEJM198306233082506.

引用本文的文献

1
Prognosis of adults and children following a first unprovoked seizure.首次无诱因发作后成人和儿童的预后。
Cochrane Database Syst Rev. 2023 Jan 23;1(1):CD013847. doi: 10.1002/14651858.CD013847.pub2.
2
Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure.首次无诱因发作的癫痫患者,即刻给予抗癫痫药物治疗与安慰剂、延迟治疗或不治疗的比较。
Cochrane Database Syst Rev. 2021 May 4;5(5):CD007144. doi: 10.1002/14651858.CD007144.pub3.
3
Clinical profile of Solitary Seizures.孤立性癫痫发作的临床特征
Med J Armed Forces India. 2004 Apr;60(2):146-8. doi: 10.1016/S0377-1237(04)80106-0. Epub 2011 Jul 21.
4
Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure.对于首次无诱因发作,立即给予抗癫痫药物治疗与给予安慰剂、延迟治疗或不治疗的比较。
Cochrane Database Syst Rev. 2016 May 6;2016(5):CD007144. doi: 10.1002/14651858.CD007144.pub2.
5
Consensus guideline for the assessment of fitness for private driving of persons with epilepsy in Korea.韩国癫痫患者私人驾驶适宜性评估的共识指南。
J Epilepsy Res. 2011 Mar 30;1(1):1-5. doi: 10.14581/jer.11001. eCollection 2011 Mar.
6
Cortical up state activity is enhanced after seizures: a quantitative analysis.皮质兴奋状态活动在癫痫发作后增强:一项定量分析。
J Clin Neurophysiol. 2010 Dec;27(6):425-32. doi: 10.1097/WNP.0b013e3181fdf8bd.
7
Can neural network able to estimate the prognosis of epilepsy patients according to risk factors?神经网络能否根据危险因素预测癫痫患者的预后?
J Med Syst. 2010 Aug;34(4):541-50. doi: 10.1007/s10916-009-9267-8. Epub 2009 Mar 28.
8
Treatment strategies after a single seizure : rationale for immediate versus deferred treatment.单次发作后的治疗策略:立即治疗与延迟治疗的理论依据
CNS Drugs. 2007;21(2):89-99. doi: 10.2165/00023210-200721020-00001.
9
Interrater agreement of the diagnosis and classification of a first seizure in childhood. The Dutch Study of Epilepsy in Childhood.儿童首次癫痫发作诊断与分类的评分者间一致性。荷兰儿童癫痫研究。
J Neurol Neurosurg Psychiatry. 2004 Feb;75(2):241-5. doi: 10.1136/jnnp.2003.015826.
10
The first unprovoked, untreated seizure in childhood: a hospital based study of the accuracy of the diagnosis, rate of recurrence, and long term outcome after recurrence. Dutch study of epilepsy in childhood.儿童期首次无诱因、未经治疗的癫痫发作:一项基于医院的关于诊断准确性、复发率及复发后长期预后的研究。荷兰儿童癫痫研究。
J Neurol Neurosurg Psychiatry. 1998 May;64(5):595-600. doi: 10.1136/jnnp.64.5.595.