Vette J K
Acta Endocrinol Suppl (Copenh). 1985;268:1-82.
Many imaging modalities are used in the investigation of the thyroid gland. In this multitude of methods, none of the applied modalities per se is able to discriminate between the benign or malignant nature of a thyroid lesion with absolute certitude. In this thesis, CT-imaging in various conditions of the thyroid gland is described. At the same time, the advantages and the risks of the application of free iodine as selective contrast agent for thyroid imaging in selective cases is studied. In chapter II a review of imaging modalities is described. A survey is given of the value of each imaging modality for the daily routine practice. In chapter III, relevant technical aspects of CT scanning with respect to the thyroid investigation are highlighted. These include technical possibilities typical for CT-scanning, dosimetric aspects and the patient preparation protocol. The CT-scan procedure is described for the neck region and the mediastinum. Chapter IV summarizes some important aspects of the iodine metabolism of which the radiologist should be aware. Chapter V describes the advantages of our scanning method in different patient groups. Evidence is obtained that CT-investigation of patients with a MEN 2-syndrome in the early assessment of tumor localization is of value. Application of CT in patients with a scintigraphically demonstrated cold nodule is shown to have consequences. Refinement of this diagnosis is possible and of additional value. The appearance of a multinodular goiter on CT is shown to be characteristic. Typical CT-features of this lesion are described which makes a strong indication in the direction of the histological diagnosis possible. With respect to the mediastinal masses of unknown origin, CT-signs of these lesions are considered. CT-examination can differentiate between goiters, benign cysts, infiltrative lesions and enlarged lymph nodes. Some attention is paid to future technical developments of CT, i.e., dual energy scanning. Early experiences are promising, especially in the field of thyroid imaging.
许多成像方式用于甲状腺的检查。在众多方法中，没有一种应用的成像方式本身能够绝对确定地区分甲状腺病变的良性或恶性性质。在本论文中，描述了甲状腺在各种情况下的CT成像。同时，研究了在特定病例中应用游离碘作为甲状腺成像选择性造影剂的优点和风险。第二章描述了成像方式的综述。给出了每种成像方式在日常实践中的价值概述。第三章强调了与甲状腺检查相关的CT扫描技术方面。这些包括CT扫描特有的技术可能性、剂量学方面和患者准备方案。描述了颈部区域和纵隔的CT扫描程序。第四章总结了放射科医生应了解的碘代谢的一些重要方面。第五章描述了我们的扫描方法在不同患者群体中的优点。有证据表明，对患有MEN 2综合征的患者进行CT检查以早期评估肿瘤定位具有价值。结果表明，对闪烁扫描显示为冷结节的患者应用CT有一定意义。这种诊断的细化是可能的且具有额外价值。显示了多结节性甲状腺肿在CT上的表现具有特征性。描述了该病变的典型CT特征，这使得在组织学诊断方向上有很强的指示作用成为可能。对于不明来源的纵隔肿块，考虑了这些病变的CT征象。CT检查可以区分甲状腺肿、良性囊肿、浸润性病变和肿大的淋巴结。还关注了CT的未来技术发展，即双能扫描。早期经验很有前景，尤其是在甲状腺成像领域。
