Kawakita Naoya, Kondo Kazuya, Toba Hiroaki, Yoneda Akiko, Takizawa Hiromitsu, Tangoku Akira
Department of Thoracic and Endocrine Surgery and Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan.
Department of Oncological Medical Services, Graduate School of Biomedical Biosciences, Tokushima University, Tokushima, Japan.
Gen Thorac Cardiovasc Surg. 2018 Apr;66(4):239-242. doi: 10.1007/s11748-017-0794-9. Epub 2017 Jun 24.
We present a case of type A thymoma with invasion of the left brachiocephalic vein and lung metastases. An 84-year-old man underwent extended thymectomy combined with left brachiocephalic vein reconstruction and resection of a lung metastasis. Histological examination showed vascular invasion by the tumor. The lung metastasis had high mitotic activity and slight nuclear enlargement, the so-called "atypical" features, but the main part of the primary tumor did not. However, the intravascular portion of the tumor had "atypical" histological features like the lung metastasis. It seems that "atypical" histological features are related to clinically malignant behavior.
我们报告一例侵犯左头臂静脉并伴有肺转移的A型胸腺瘤病例。一名84岁男性接受了扩大胸腺切除术，同时进行了左头臂静脉重建和肺转移灶切除。组织学检查显示肿瘤存在血管侵犯。肺转移灶有高有丝分裂活性和轻微核增大，即所谓的“非典型”特征，但原发肿瘤的主要部分没有。然而，肿瘤的血管内部分具有与肺转移灶相似的“非典型”组织学特征。似乎“非典型”组织学特征与临床恶性行为有关。
