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[中国甘肃省流感的季节特征与病原分布研究]

[Study on seasonal characteristics and pathogenic distribution of influenza in Gansu province of China].

作者信息

Yang X T, Liu X F, He J, Yu D S, Liu D P, Li H Y, Li B D, Bai Y N

机构信息

Institute for Communicable Disease Control and Prevention, Gansu Provincial Center for Disease Control and Prevention, Lanzhou 730000, China; Institute of Epidemiology and Biostatistics, School of Public Health, Lanzhou University, Lanzhou 730000, China.

Institute for Communicable Disease Control and Prevention, Gansu Provincial Center for Disease Control and Prevention, Lanzhou 730000, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Jun 10;38(6):763-766. doi: 10.3760/cma.j.issn.0254-6450.2017.06.015.

DOI:10.3760/cma.j.issn.0254-6450.2017.06.015
PMID:28647979
Abstract

To study the epidemiologic characteristics of influenza in Gansu province of China and to optimize the related vaccination program. Weekly influenza surveillance data from the first week of 2010 to the fortieth week of 2016 were collected, in Gansu province. (2) test was used to compare the differences of nucleic acid positive rate and the virus types in the four seasons. Time series seasonal decomposition (TSSD) was used to explore seasonal patterns and characteristics of influenza epidemics in Gansu. 59 791 specimens were tested, with 8 501 positive for influenza virus and positive rates as 14.22. Types A(H1N1)pdm09, A(H3N2) and type B were accounted for 98.76 of all the positive specimens. Proportions of the positive rate of influenza virus appeared in spring, summer, autumn and winter were 15.12, 0.98, 4.02 and 24.26 respectively. The predominant type of virus in autumn and winter was A(H3N2), with B mainly in spring. Influenza in Gansu province showed typical single-peak type distribution, with epidemic peak appeared from December to next January. The type A(H3N2) related peak appeared the earliest, followed by A(H1N1) pdm09, with type B the latest. Peaks and the duration of influenza seasonal epidemics were related to the types of dominant strains. Annual influenza vaccination campaigns should start in October, to provide effective protection during the epidemic period.

摘要

研究中国甘肃省流感的流行病学特征并优化相关疫苗接种计划。收集了甘肃省2010年第一周至2016年第四十周的每周流感监测数据。(2)采用检验比较四季中核酸阳性率和病毒类型的差异。运用时间序列季节分解法(TSSD)探究甘肃省流感流行的季节模式和特征。共检测了59791份标本,其中8501份流感病毒呈阳性,阳性率为14.22%。甲型(H1N1)pdm09、甲型(H3N2)和乙型流感病毒占所有阳性标本的98.76%。流感病毒阳性率在春、夏、秋、冬四季出现的比例分别为15.12%、0.98%、4.02%和24.26%。秋冬季节的主要病毒类型为甲型(H3N2),春季主要为乙型。甘肃省流感呈现典型的单峰型分布,流行高峰出现在12月至次年1月。甲型(H3N2)相关的高峰出现最早,其次是甲型(H1N1)pdm09,乙型最晚。流感季节性流行的高峰和持续时间与优势毒株类型有关。年度流感疫苗接种活动应在10月开始,以便在流行期间提供有效保护。

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