Luo X Y, Zhang F X
Department of Vascular Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038 , China.
Zhonghua Yi Xue Za Zhi. 2017 Jun 27;97(24):1875-1877. doi: 10.3760/cma.j.issn.0376-2491.2017.24.007.
To assess the validity of Caprini risk assessment model in prediction of venous thromboembolism in Chinese hospitalized patients in a general hospital. Medical record review was performed in Beijing Shijitan Hosital for all eligible hospitalized patients who underwent screening for venous thromboembolism between January and December 2015. The Caprini score of patients with or without venous thromboemboilism and incidence of venous thromboembolism in patients with various Caprini risk levels, surgery and medical patients was compared. A total of 6 966 inpatients were enrolled. Three hundred and ninety-six patients developed venous thromboembolism. The Caprini median score of patients with venous thromboemboilism was 5 (3-7), which higher than 3(2-5) of patients without venous thromboembolism(=-13.68, <0.01). Incidence of venous thromboembolism of patients in low, moderate, high, highest risk level was 1.0%, 1.8%, 5.7%, 10.6%, respectively. There was no statistically significant difference of incidence between low and moderate risk patients (=1.88, 95%: 0.89-3.99, >0.05), but significant difference between moderate and high risk (=3.23, 95%: 2.06-5.06, <0.01), high and highest risk patients (=1.97, 95%: 1.59-2.45, <0.01). There was no incidence difference of venous thromboembolism between surgery and medical patients in the same Caprini level of low (χ(2)=3.58 , >0.05), moderate(χ(2)=2.89, >0.05), high(χ(2)=0.46, >0.05), highest risk(χ(2)=1.61, >0.05). Caprini risk assessment model can effectively predict the occurence of venous thromboembolism in Chinese hospitalized patients with high risk of VTE(Caprini score >2)in a general hospital.
评估Caprini风险评估模型在综合医院中国住院患者静脉血栓栓塞预测中的有效性。对北京世纪坛医院2015年1月至12月期间所有接受静脉血栓栓塞筛查的符合条件的住院患者进行病历审查。比较了有或无静脉血栓栓塞患者的Caprini评分以及不同Caprini风险水平、手术患者和内科患者的静脉血栓栓塞发生率。共纳入6966例住院患者。396例患者发生静脉血栓栓塞。发生静脉血栓栓塞患者的Caprini中位数评分为5（3 - 7），高于未发生静脉血栓栓塞患者的3（2 - 5）（=-13.68，<0.01）。低、中、高、极高风险水平患者的静脉血栓栓塞发生率分别为1.0%、1.8%、5.7%、10.6%。低风险和中风险患者之间的发生率无统计学显著差异（=1.88，95%：0.89 - 3.99，>0.05），但中风险和高风险之间有显著差异（=3.23，95%：2.06 - 5.06，<0.01），高风险和极高风险患者之间有显著差异（=1.97，95%：1.59 - 2.45，<0.01）。在相同Caprini低风险水平（χ(2)=3.58，>0.05）、中风险水平（χ(2)=2.89，>0.05）、高风险水平（χ(2)=0.46，>0.05）、极高风险水平（χ(2)=1.61，>0.05）下，手术患者和内科患者的静脉血栓栓塞发生率无差异。Caprini风险评估模型可有效预测综合医院中具有静脉血栓栓塞高风险（Caprini评分>2）的中国住院患者静脉血栓栓塞的发生情况。
