在NanoSIMS50L上使用七个探测器准同时采集九种二次离子：应用于生物样品。
Quasi-simultaneous acquisition of nine secondary ions with seven detectors on NanoSIMS50L: application to biological samples.
作者信息
Guillermier Christelle, Steinhauser Matthew L, Lechene Claude P
机构信息
Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
National Resource for Imaging Mass Spectrometry (NRIMS), Cambridge, MA, USA.
出版信息
Surf Interface Anal. 2014 Nov;46(Suppl 1):150-153. doi: 10.1002/sia.5496. Epub 2014 May 7.
Abstract
We employed a method of electrostatic peak switching allowing for the quasi-simultaneous measurement of O, O, CH, CD,CN, CN, CN, P, and S with the NanoSIMS 50L instrument to derive ratios for D/H, C/C, O/O, and N/N from biological samples. This approach involves two steps: (i) derivation of the D/H ratio from measurements of CD and CH and (ii) switching of the voltage on deflection plates located in front of two detectors. The method is reliable and easy to set up compared with the magnetic peak-switching mode usually used to perform this type of analysis.
摘要
我们采用了一种静电峰切换方法，通过NanoSIMS 50L仪器对O、O、CH、CD、CN、CN、CN、P和S进行准同步测量，以从生物样品中得出D/H、C/C、O/O和N/N的比率。该方法包括两个步骤：(i) 通过测量CD和CH得出D/H比率；(ii) 切换位于两个探测器前方的偏转板上的电压。与通常用于进行此类分析的磁峰切换模式相比，该方法可靠且易于设置。
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