Cambridge Breast Unit, Addenbrookes Hospital & University of Cambridge, Faculty of Medical Sciences, Anglia Ruskin University, Cambridge, UK.
Division of Surgical Oncology, Dale H Dorn Chair in Surgery, University of Texas Health Science Centre, TX, USA.
Future Oncol. 2017 Jun;13(15):1291-1295. doi: 10.2217/fon-2017-0088. Epub 2017 Jun 26.
The 39th annual San Antonio Breast Cancer Symposium (SABCS) was convened in San Antonio, Texas, on 9-13 December 2016. More than 7000 clinicians and scientists from around the world participated in the symposium which featured a range of presentations and keynote talks pertaining to breast cancer screening, prevention, locoregional and systemic therapies. This two-part report highlights a selection of important studies presented at this premier breast cancer event with Part 1 focusing onmetastatic breast cancer, extended endocrine therapy and the prognostic significance of BRCA1/2 gene mutations. The second part of this report will discuss a range of topics including anti-HER2 directed treatments, the impact of radiotherapy on implant and autologous flap based reconstruction, biological risk predictors for ductal carcinoma-in situ (DCIS), longer term effects of dietary fat modification and the influence of aromatase inhibitors on endothelial cell function.
第 39 届圣安东尼奥乳腺癌研讨会（SABCS）于 2016 年 12 月 9 日至 13 日在德克萨斯州圣安东尼奥市召开。来自世界各地的 7000 多名临床医生和科学家参加了本次研讨会，研讨会的内容涉及乳腺癌筛查、预防、局部和全身治疗等多个方面。本报告的两部分重点介绍了在这一乳腺癌盛会上展示的一些重要研究，第一部分主要讨论转移性乳腺癌、延长内分泌治疗以及 BRCA1/2 基因突变的预后意义。本报告的第二部分将讨论包括抗 HER2 靶向治疗、放疗对植入物和自体皮瓣重建的影响、导管原位癌（DCIS）的生物学风险预测因子、饮食脂肪改良的长期影响以及芳香酶抑制剂对内皮细胞功能的影响等多个主题。
