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尿动力学压力性尿失禁女性患者尿道横纹括约肌形态的超声评估

Ultrasonographic Evaluation of the Urethral Rhabdosphincter Morphology in Female Patients With Urodynamic Stress Incontinence.

作者信息

Zacharakis Dimitrios, Grigoriadis Themos, Pitsouni Eleni, Domali Ekaterini, Protopapas Athanasios, Athanasiou Stavros

机构信息

From the First Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens, "Alexandra" Hospital, Athens, Greece.

出版信息

Female Pelvic Med Reconstr Surg. 2017 Jul/Aug;23(4):267-271. doi: 10.1097/SPV.0000000000000355.

Abstract

OBJECTIVES

During the last 2 decades, ultrasonography has been proposed for the morphologic evaluation of the urethral rhabdosphincter. The aims of this study were to evaluate the feasibility of a simple sonographic technique for the assessment of the urethral rhabdosphincter morphology by using a 2-dimensional (2D) transvaginal transducer and to evaluate any associations between the sonographic parameters of rhabdosphincter morphology with the presence of urodynamic stress incontinence (USI).

METHODS

This was a prospective study of women who underwent urodynamic studies and an introital 2D ultrasonography and divided in 2 groups based on the presence or absence of USI. Measurements included rhabdosphincter thickness at the 3-o'clock (right) and 9-o'clock (left) positions and the rhabdosphincter outer (Π) and inner circumference (π). Based on these values, the mean thickness of the rhabdosphincter (R + L / 2), the rhabdosphincter differential perimeter (Π - π), and area (A - α) were also calculated.

RESULTS

Statistical analysis showed that women with a rhabdosphincter area of less than 0.65 cm, mean thickness of less than 0.24 cm, and differential perimeter of less than 1.08 cm had 3.98, 5.67, and 5.41 times greater odds for USI, respectively. Receiver operating characteristic curve analysis results showed that the optimal cutoff values for the prediction of USI from rhabdosphincter thickness, differential perimeter. and surface area were 0.24 cm (79.6% sensitivity, 63.4% specificity), 1.08 cm (70.8% sensitivity and 69.1% specificity), and 0.65 cm (71.9% sensitivity, 57.1% specificity), respectively.

CONCLUSIONS

Introital ultrasonography with a 2D transvaginal probe allowed the visualization of the urethral rhabdosphincter morphology in greater than 90% of the cases. Sonographic measurements showed that patients with USI had a thinner urethral rhabdosphincter than did women with a normal sphincteric mechanism.

摘要

目的

在过去20年中,超声检查已被用于尿道横纹括约肌的形态学评估。本研究的目的是评估使用二维(2D)经阴道探头的简单超声技术评估尿道横纹括约肌形态的可行性,并评估横纹括约肌形态的超声参数与尿动力学压力性尿失禁(USI)的存在之间的任何关联。

方法

这是一项对接受尿动力学研究和阴道入口二维超声检查的女性进行的前瞻性研究,根据是否存在USI将其分为两组。测量包括3点钟(右侧)和9点钟(左侧)位置的横纹括约肌厚度以及横纹括约肌外周(Π)和内周(π)。基于这些值,还计算了横纹括约肌的平均厚度(R + L / 2)、横纹括约肌周长差(Π - π)和面积(A - α)。

结果

统计分析表明,横纹括约肌面积小于0.65 cm、平均厚度小于0.24 cm和周长差小于1.08 cm的女性发生USI的几率分别高3.98、5.67和5.41倍。受试者工作特征曲线分析结果表明,根据横纹括约肌厚度、周长差和表面积预测USI的最佳截断值分别为0.24 cm(敏感性79.6%,特异性63.4%)、1.08 cm(敏感性70.8%,特异性69.1%)和0.65 cm(敏感性71.9%,特异性57.1%)。

结论

使用二维经阴道探头进行阴道入口超声检查可在90%以上的病例中显示尿道横纹括约肌形态。超声测量表明,与括约肌机制正常的女性相比,USI患者的尿道横纹括约肌更薄。

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